Original Research

Published on 30 Apr 2021

Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain

in Chemical Biology

Camila A. Cotrim
Russell J. Jarrott
Andrew E. Whitten
Hassanul G. Choudhury
David Drew
Jennifer L. Martin

Frontiers in Chemistry

doi 10.3389/fchem.2021.667803

5,197 views
11 citations

Original Research

Published on 30 Apr 2021

Protein-Inorganic Hybrid Nanoflowers as Efficient Biomimetic Antibiotics in the Treatment of Bacterial Infection

in Chemical Biology

Ying Zhou
Ying Li
Yunwei Fei
Mingrui Zhang
Shuang Wang
Fuqiu Li
Xingfu Bao

Frontiers in Chemistry

doi 10.3389/fchem.2021.681566

4,685 views
12 citations

Review

Published on 29 Apr 2021

Isocyanides: Promising Functionalities in Bioorthogonal Labeling of Biomolecules

in Chemical Biology

Yuchen Zhu
Jia-Yu Liao
Linghui Qian

Frontiers in Chemistry

doi 10.3389/fchem.2021.670751

6,032 views
6 citations

Review

Published on 29 Apr 2021

Peptidyl Activity-Based Probes for Imaging Serine Proteases

in Chemical Biology

Paulina Kasperkiewicz

Frontiers in Chemistry

doi 10.3389/fchem.2021.639410

9,450 views
8 citations

Original Research

Published on 29 Apr 2021

A Synthetic Phospholipid Derivative Mediates Ion Transport Across Lipid Bilayers

in Chemical Biology

Chenxi Wang
Huiting Yang
Yanxin Xiang
Shihao Pang
Chunyan Bao
Linyong Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2021.667472

3,020 views
5 citations

Original Research

Published on 28 Apr 2021

Pomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs

in Chemical Biology

Annalisa Tito
Antonio Colantuono
Luciano Pirone
Emilia Pedone
Daniela Intartaglia
Giuliana Giamundo
Ivan Conte
Paola Vitaglione
Fabio Apone

Frontiers in Chemistry

doi 10.3389/fchem.2021.638187

44,627 views
73 citations

Mini Review

Published on 23 Apr 2021

Recent Advances on Sorting Methods of High-Throughput Droplet-Based Microfluidics in Enzyme Directed Evolution

in Chemical Biology

Xiaozhi Fu
Yueying Zhang
Qiang Xu
Xiaomeng Sun
Fanda Meng

Frontiers in Chemistry

doi 10.3389/fchem.2021.666867

13,678 views
29 citations

Original Research

Published on 22 Apr 2021

Development of Fluorescent and Biotin Probes Targeting NLRP3

in Chemical Biology

Tim Keuler
Karl Gatterdam
Anil Akbal
Marta Lovotti
Michael Marleaux
Matthias Geyer
Eicke Latz
Michael Gütschow

Frontiers in Chemistry

doi 10.3389/fchem.2021.642273

5,959 views
10 citations

Original Research

Published on 21 Apr 2021

Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations

in Chemical Biology

Jon I. Quintana
Sandra Delgado
Reyes Núñez-Franco
F. Javier Cañada
Gonzalo Jiménez-Osés
Jesús Jiménez-Barbero
Ana Ardá

Frontiers in Chemistry

doi 10.3389/fchem.2021.664097

3,744 views
11 citations

Review

Published on 20 Apr 2021

From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation

in Chemical Biology

Carlotta Cecchini
Sara Pannilunghi
Sébastien Tardy
Leonardo Scapozza

Frontiers in Chemistry

doi 10.3389/fchem.2021.672267

46,428 views
98 citations

Review

Published on 15 Apr 2021

Modular Approaches to Synthesize Activity- and Affinity-Based Chemical Probes

in Chemical Biology

Antonie J. van der Zouwen
Martin D. Witte

Frontiers in Chemistry

doi 10.3389/fchem.2021.644811

7,343 views
11 citations

Original Research

Published on 14 Apr 2021

New Quinolinone O-GlcNAc Transferase Inhibitors Based on Fragment Growth

in Chemical Biology

Matjaž Weiss
Elena M. Loi
Maša Sterle
Cyril Balsollier
Tihomir Tomašič
Roland J. Pieters
Martina Gobec
Marko Anderluh

Frontiers in Chemistry

doi 10.3389/fchem.2021.666122

5,630 views
7 citations

Original Research

Published on 14 Apr 2021

Improving the Thermostability and Activity of Transaminase From Aspergillus terreus by Charge-Charge Interaction

in Chemical Biology

Jia-Ren Cao
Fang-Fang Fan
Chang-Jiang Lv
Hong-Peng Wang
Ye Li
Sheng Hu
Wei-Rui Zhao
Hai-Bin Chen
Jun Huang
Le-He Mei

Frontiers in Chemistry

doi 10.3389/fchem.2021.664156

8,539 views
32 citations

Original Research

Published on 14 Apr 2021

In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes

in Chemical Biology

Yentl Van Rymenant
Muhammet Tanc
Roos Van Elzen
An Bracke
Olivier De Wever
Koen Augustyns
Anne-Marie Lambeir
Mark Kockx
Ingrid De Meester
Pieter Van Der Veken

Frontiers in Chemistry

doi 10.3389/fchem.2021.640566

7,623 views
11 citations

Mini Review

Published on 13 Apr 2021

Application of the Inverse-Electron-Demand Diels-Alder Reaction for Metabolic Glycoengineering

in Chemical Biology

Lisa Maria Haiber
Markus Kufleitner
Valentin Wittmann

Frontiers in Chemistry

doi 10.3389/fchem.2021.654932

6,351 views
16 citations

Mini Review

Published on 12 Apr 2021

Chemical Glycosylation and Its Application to Glucose Homeostasis-Regulating Peptides

in Chemical Biology

Chaitra Chandrashekar
Mohammed Akhter Hossain
John D. Wade

Frontiers in Chemistry

doi 10.3389/fchem.2021.650025

6,376 views
17 citations

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Articles

Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain

Protein-Inorganic Hybrid Nanoflowers as Efficient Biomimetic Antibiotics in the Treatment of Bacterial Infection

Isocyanides: Promising Functionalities in Bioorthogonal Labeling of Biomolecules

Peptidyl Activity-Based Probes for Imaging Serine Proteases

A Synthetic Phospholipid Derivative Mediates Ion Transport Across Lipid Bilayers

Pomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs

Recent Advances on Sorting Methods of High-Throughput Droplet-Based Microfluidics in Enzyme Directed Evolution

Development of Fluorescent and Biotin Probes Targeting NLRP3

Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations

From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation

Modular Approaches to Synthesize Activity- and Affinity-Based Chemical Probes

New Quinolinone O-GlcNAc Transferase Inhibitors Based on Fragment Growth

Improving the Thermostability and Activity of Transaminase From Aspergillus terreus by Charge-Charge Interaction

In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes

Application of the Inverse-Electron-Demand Diels-Alder Reaction for Metabolic Glycoengineering

Chemical Glycosylation and Its Application to Glucose Homeostasis-Regulating Peptides