Frontiers in Chemistry | Chemical Biology

Original Research

Published on 04 Aug 2021

Designed Artificial Protein Heterodimers With Coupled Functions Constructed Using Bio-Orthogonal Chemistry

in Chemical Biology

Rachel L. Johnson
Hayley G. Blaber
Tomas Evans
Harley L. Worthy
Jacob R. Pope
D. Dafydd Jones

Frontiers in Chemistry

doi 10.3389/fchem.2021.733550

4,236 views
2 citations

Original Research

Published on 04 Aug 2021

A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues

in Chemical Biology

Nadiia Kovalenko
Georgina K. Howard
Jonathan A. Swain
Yann Hermant
Alan J. Cameron
Gregory M. Cook
Scott A. Ferguson
Louise A. Stubbing
Paul W. R. Harris
Margaret A. Brimble

Frontiers in Chemistry

doi 10.3389/fchem.2021.687875

5,245 views
8 citations

Mini Review

Published on 30 Jul 2021

The Archaeal Na+/Ca2+ Exchanger (NCX_Mj) as a Model of Ion Transport for the Superfamily of Ca2+/CA Antiporters

in Chemical Biology

Daniel Khananshvili

Frontiers in Chemistry

doi 10.3389/fchem.2021.722336

2,915 views
10 citations

Original Research

Published on 29 Jul 2021

Chemical Synthesis of the Sec-To-Cys Homologue of Human Selenoprotein F and Elucidation of Its Disulfide-pairing Mode

in Chemical Biology

Peisi Liao
Chunmao He

Frontiers in Chemistry

doi 10.3389/fchem.2021.735149

3,389 views
9 citations

Original Research

Published on 26 Jul 2021

Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit

in Chemical Biology

Chris E. Cooper
Matthew Bird
XiaoBo Sheng
Ji-Won Choi
Gary G.A. Silkstone
Michelle Simons
Natalie Syrett
Riccardo Piano
Luca Ronda
Stefano Bettati

Frontiers in Chemistry

doi 10.3389/fchem.2021.707797

9,347 views
6 citations

Review

Published on 19 Jul 2021

Radical SAM Enzymes and Ribosomally‐Synthesized and Post‐translationally Modified Peptides: A Growing Importance in the Microbiomes

in Chemical Biology

Alhosna Benjdia
Olivier Berteau

Frontiers in Chemistry

doi 10.3389/fchem.2021.678068

8,671 views
23 citations

Mini Review

Published on 19 Jul 2021

Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

in Chemical Biology

Pedro J. Hernando
Simone Dedola
María J. Marín
Robert A. Field

Frontiers in Chemistry

doi 10.3389/fchem.2021.668509

5,359 views
11 citations

Original Research

Published on 16 Jul 2021

Construction of T7-Like Expression System in Pseudomonas putida KT2440 to Enhance the Heterologous Expression Level

in Chemical Biology

Tianxin Liang
Jun Sun
Shuyun Ju
Shenyi Su
Lirong Yang
Jianping Wu

Frontiers in Chemistry

doi 10.3389/fchem.2021.664967

6,647 views
10 citations

Original Research

Published on 15 Jul 2021

In Situ Generated Novel 1H MRI Reporter for β-Galactosidase Activity Detection and Visualization in Living Tumor Cells

in Chemical Biology

Shuo Gao
Lei Zhao
Zhiqiang Fan
Vikram D. Kodibagkar
Li Liu
Hanqin Wang
Hong Xu
Mingli Tu
Bifu Hu
Chuanbin Cao

Frontiers in Chemistry

doi 10.3389/fchem.2021.709581

4,054 views
7 citations

Original Research

Published on 14 Jul 2021

Quantification of Intact O-Glycopeptides on Haptoglobin in Sera of Patients With Hepatocellular Carcinoma and Liver Cirrhosis

in Chemical Biology

Hong Shu
Lei Zhang
Yiwei Chen
Yijie Guo
Limin Li
Fanghua Chen
Zhao Cao
Guoquan Yan
Chunlai Lu
Chao Liu

Frontiers in Chemistry

doi 10.3389/fchem.2021.705341

3,043 views
8 citations

Original Research

Published on 12 Jul 2021

Hypochlorite-Activated Fluorescence Emission and Antibacterial Activities of Imidazole Derivatives for Biological Applications

in Chemical Biology

Thanh Chung Pham
Van-Nghia Nguyen
Yeonghwan Choi
Dongwon Kim
Ok-Sang Jung
Dong Joon Lee
Hak Jun Kim
Myung Won Lee
Juyoung Yoon
Hwan Myung Kim

Frontiers in Chemistry

doi 10.3389/fchem.2021.713078

3,990 views
7 citations

Review

Published on 07 Jul 2021

α-Synuclein: An All-Inclusive Trip Around its Structure, Influencing Factors and Applied Techniques

in Chemical Biology

Nicolò Bisi
Lucia Feni
Kaliroi Peqini
Helena Pérez-Peña
Sandrine Ongeri
Stefano Pieraccini
Sara Pellegrino

Frontiers in Chemistry

doi 10.3389/fchem.2021.666585

14,128 views
52 citations

Review

Published on 30 Jun 2021

Targeting Protein Kinases Degradation by PROTACs

in Chemical Biology

Fei Yu
Ming Cai
Liang Shao
Jihong Zhang

Frontiers in Chemistry

doi 10.3389/fchem.2021.679120

15,187 views
38 citations

Original Research

Published on 29 Jun 2021

Computational Modeling of C-Terminal Tails to Predict the Calcium-Dependent Secretion of Endoplasmic Reticulum Resident Proteins

in Chemical Biology

Kathleen A. Trychta
Bing Xie
Ravi Kumar Verma
Min Xu
Lei Shi
Brandon K. Harvey

Frontiers in Chemistry

doi 10.3389/fchem.2021.689608

5,069 views
6 citations

Original Research

Published on 28 Jun 2021

Cyclic Dipeptides Formation From Linear Dipeptides Under Potentially Prebiotic Earth Conditions

in Chemical Biology

Yeting Guo
Jianxi Ying
Dongru Sun
Yumeng Zhang
Minyang Zheng
Ruiwen Ding
Yan Liu
Yufen Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2021.675821

4,747 views
8 citations

Review

Published on 25 Jun 2021

Chemistry-Assisted Proteomic Profiling of O-GlcNAcylation

in Chemical Biology

Qiang Zhu
Wen Yi

Frontiers in Chemistry

doi 10.3389/fchem.2021.702260

4,567 views
11 citations