Frontiers in Chemistry | Chemical Biology

Original Research

Published on 22 Oct 2021

Site-Specific Protein Modifications by an Engineered Asparaginyl Endopeptidase from Viola canadensis

in Chemical Biology

Yu Chen
Dingpeng Zhang
Xiaohong Zhang
Zhen Wang
Chuan-Fa Liu
James P. Tam

Frontiers in Chemistry

doi 10.3389/fchem.2021.768854

4,346 views
7 citations

Original Research

Published on 14 Oct 2021

Antimicrobial Peptides-Loaded Hydroxyapatite Microsphere With Different Hierarchical Structures for Enhanced Drug Loading, Sustained Release and Antibacterial Activity

in Chemical Biology

Dandan Hong
Jingjing Wu
Xuemin Xiao
Xueyang Li
Dong Xu
Chang Du

Frontiers in Chemistry

doi 10.3389/fchem.2021.747665

3,116 views
7 citations

Original Research

Published on 12 Oct 2021

The Metabolic Chemical Reporter Ac46AzGal Could Incorporate Intracellular Protein Modification in the Form of UDP-6AzGlc Mediated by OGT and Enzymes in the Leloir Pathway

in Chemical Biology

Jiajia Wang
Biao Dou
Lu Zheng
Wei Cao
Peiyu Dong
Yingyi Chen
Xueke Zeng
Yinhang Wen
Wenxuan Pan
Jing Ma

Frontiers in Chemistry

doi 10.3389/fchem.2021.708306

2,542 views
3 citations

Original Research

Published on 27 Sep 2021

Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction

in Chemical Biology

Jiacheng Xiong
Yusen Xiang
Ziming Huang
Xiaohong Liu
Mengge Wang
Guangbo Ge
Hongzhuan Chen
Jianrong Xu
Mingyue Zheng
Lili Chen

Frontiers in Chemistry

doi 10.3389/fchem.2021.740702

5,718 views
21 citations

Original Research

Published on 24 Sep 2021

A Linkage-specific Sialic Acid Labeling Strategy Reveals Different Site-specific Glycosylation Patterns in SARS-CoV-2 Spike Protein Produced in CHO and HEK Cell Substrates

in Chemical Biology

Qiong Wang
Yan Wang
Shuang Yang
Changyi Lin
Lateef Aliyu
Yiqun Chen
Lisa Parsons
Yuan Tian
Hongpeng Jia
Andrew Pekosz

Frontiers in Chemistry

doi 10.3389/fchem.2021.735558

7,409 views
16 citations

Original Research

Published on 15 Sep 2021

Acetylated Thioredoxin Reductase 1 Resists Oxidative Inactivation

in Chemical Biology

David. E. Wright
Nikolaus Panaseiko
Patrick O’Donoghue

Frontiers in Chemistry

doi 10.3389/fchem.2021.747236

3,375 views
7 citations

Original Research

Published on 14 Sep 2021

Total Synthesis and Antimicrobial Evaluation of Pagoamide A

in Chemical Biology

Cheng-Han Wu
John Chu

Frontiers in Chemistry

doi 10.3389/fchem.2021.741290

6,242 views
5 citations

Original Research

Published on 14 Sep 2021

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1

in Chemical Biology

Stefanie Kickinger
Maria E. K. Lie
Akihiro Suemasa
Anas Al-Khawaja
Koichi Fujiwara
Mizuki Watanabe
Kristine S. Wilhelmsen
Christina B. Falk-Petersen
Bente Frølund
Satoshi Shuto

Frontiers in Chemistry

doi 10.3389/fchem.2021.736457

3,812 views
7 citations

Editorial

Published on 09 Sep 2021

Editorial: Development and Applications of New Activity-Based Probes

in Chemical Biology

Galia Blum
Steven H. L. Verhelst
Xiaowei Ma

Frontiers in Chemistry

doi 10.3389/fchem.2021.754294

2,262 views
3 citations

Original Research

Published on 06 Sep 2021

O-Glycosylation Landscapes of SARS-CoV-2 Spike Proteins

in Chemical Biology

Yong Zhang
Wanjun Zhao
Yonghong Mao
Yaohui Chen
Shanshan Zheng
Wei Cao
Jingqiang Zhu
Liqiang Hu
Meng Gong
Jingqiu Cheng

Frontiers in Chemistry

doi 10.3389/fchem.2021.689521

7,100 views
34 citations

Editorial

Published on 31 Aug 2021

Editorial: Molecular Studies of Covid-19 Chemistry

in Chemical Biology

Domenica Capasso
Sonia Di Gaetano
Chandrabose Selvaraj
Emilia Pedone

Frontiers in Chemistry

doi 10.3389/fchem.2021.729142

2,372 views

Review

Published on 23 Aug 2021

Identification and Characteristics of Fusion Peptides Derived From Enveloped Viruses

in Chemical Biology

Camille Lozada
Thomas M. A. Barlow
Simon Gonzalez
Nadège Lubin-Germain
Steven Ballet

Frontiers in Chemistry

doi 10.3389/fchem.2021.689006

15,211 views
27 citations

Mini Review

Published on 19 Aug 2021

Sulfoxide Reductases and Applications in Biocatalytic Preparation of Chiral Sulfoxides: A Mini-Review

in Chemical Biology

Tao Peng
Xiaoling Cheng
Yongzheng Chen
Jiawei Yang

Frontiers in Chemistry

doi 10.3389/fchem.2021.714899

5,474 views
20 citations

Editorial

Published on 12 Aug 2021

Editorial: Secondary Metabolites and Peptides as Unique Natural Reservoirs of New Therapeutic Leads for Treatment of Cancer and Microbial Infections

in Chemical Biology

Maria Luisa Mangoni
Anirban Bhunia
Bruno Botta
Francesca Ghirga

Frontiers in Chemistry

doi 10.3389/fchem.2021.748180

1,752 views
1 citation

Review

Published on 12 Aug 2021

Strategies of Detecting Bacteria Using Fluorescence-Based Dyes

in Chemical Biology

Shin A Yoon
Sun Young Park
Yujin Cha
Lavanya Gopala
Min Hee Lee

Frontiers in Chemistry

doi 10.3389/fchem.2021.743923

45,543 views
55 citations

Original Research

Published on 09 Aug 2021

Wobble Editing of Cre-box by Unspecific CRISPR/Cas9 Causes CCR Release and Phenotypic Changes in Bacillus pumilus

in Chemical Biology

Yingxiang Wang
Linfeng Cao
Meiying Bi
Sicheng Wang
Meiting Chen
Xingyu Chen
Ming Ying
Lei Huang

Frontiers in Chemistry

doi 10.3389/fchem.2021.717609

2,454 views
4 citations