Original Research

Published on 04 May 2022

Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening

in Chemical Biology

Sabrina R. Mackinnon
Gustavo A. Bezerra
Tobias Krojer
Tamas Szommer
Frank von Delft
Paul E. Brennan
Wyatt W. Yue

Frontiers in Chemistry

doi 10.3389/fchem.2022.844598

4,415 views
3 citations

Original Research

Published on 28 Apr 2022

3D Single Molecule Super-Resolution Microscopy of Whole Nuclear Lamina

in Chemical Biology

Ashley M. Rozario
Alison Morey
Cade Elliott
Brendan Russ
Donna R. Whelan
Stephen J. Turner
Toby D. M. Bell

Frontiers in Chemistry

doi 10.3389/fchem.2022.863610

4,944 views
8 citations

Original Research

Published on 27 Apr 2022

Novel Insights Into the Sulfated Glucuronic Acid-Based Anti-SARS-CoV-2 Mechanism of Exopolysaccharides From Halophilic Archaeon Haloarcula hispanica

in Chemical Biology

Yueqiang Xu
Yan Li
Xin You
Caixia Pei
Zhuo Wang
Siming Jiao
Xin Zhao
Xuan Lin
Yang Lü
Cheng Jin

Frontiers in Chemistry

doi 10.3389/fchem.2022.871509

2,999 views
7 citations

Review

Published on 14 Apr 2022

Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review

in Chemical Biology

Jia Zheng
Wei Zhang
Linfeng Li
Yi He
Yue Wei
Yongjun Dang
Shenyou Nie
Zufeng Guo

Frontiers in Chemistry

doi 10.3389/fchem.2022.860985

14,074 views
44 citations

Original Research

Published on 13 Apr 2022

Evaluation of Potential DnaK Modulating Proline-Rich Antimicrobial Peptides Identified by Computational Screening

in Chemical Biology

Thomas N. G. Handley
Wenyi Li
Nicholas G. Welch
Neil M. O’Brien-Simpson
Mohammed Akhter Hossain
John D. Wade

Frontiers in Chemistry

doi 10.3389/fchem.2022.875233

2,095 views
3 citations

Review

Published on 13 Apr 2022

Strategies for Glycoengineering Therapeutic Proteins

in Chemical Biology

Kris Dammen-Brower
Paige Epler
Stanley Zhu
Zachary J. Bernstein
Paul R. Stabach
Demetrios T. Braddock
Jamie B. Spangler
Kevin J. Yarema

Frontiers in Chemistry

doi 10.3389/fchem.2022.863118

12,635 views
33 citations

Original Research

Published on 08 Apr 2022

Mucin-Type O-Glycosylation Proximal to β-Secretase Cleavage Site Affects APP Processing and Aggregation Fate

in Chemical Biology

YashoNandini Singh
Deepika Regmi
David Ormaza
Ramya Ayyalasomayajula
Nancy Vela
Gustavo Mundim
Deguo Du
Dmitriy Minond
Maré Cudic

Frontiers in Chemistry

doi 10.3389/fchem.2022.859822

3,605 views
2 citations

Original Research

Published on 08 Apr 2022

The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage

in Chemical Biology

Anja Greule
Thierry Izoré
Daniel Machell
Mathias H. Hansen
Melanie Schoppet
James J. De Voss
Louise K. Charkoudian
Ralf B. Schittenhelm
Jeffrey R. Harmer
Max J. Cryle

Frontiers in Chemistry

doi 10.3389/fchem.2022.868240

2,442 views
7 citations

Original Research

Published on 24 Mar 2022

Studying Acetylation of Aconitase Isozymes by Genetic Code Expansion

in Chemical Biology

Jessica Araujo
Sara Ottinger
Sumana Venkat
Qinglei Gan
Chenguang Fan

Frontiers in Chemistry

doi 10.3389/fchem.2022.862483

2,804 views
7 citations

Mini Review

Published on 24 Mar 2022

Genetics Behind the Glycosylation Patterns in the Biosynthesis of Dalbaheptides

in Chemical Biology

Oleksandr Yushchuk
Kseniia Zhukrovska
Francesca Berini
Victor Fedorenko
Flavia Marinelli

Frontiers in Chemistry

doi 10.3389/fchem.2022.858708

2,664 views
4 citations

Original Research

Published on 16 Mar 2022

Synthesis and Characterization of Phenylboronic Acid-Modified Insulin With Glucose-Dependent Solubility

in Chemical Biology

Nai-Pin Lin
Nan Zheng
Landa Purushottam
Yi Wolf Zhang
Danny Hung-Chieh Chou

Frontiers in Chemistry

doi 10.3389/fchem.2022.859133

3,054 views
4 citations

Original Research

Published on 15 Mar 2022

An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates

in Chemical Biology

Nitin A. Patil
Varsha J. Thombare
Rong Li
Xiaoji He
Jing Lu
Heidi H. Yu
Hasini Wickremasinghe
Kavya Pamulapati
Mohammad A. K. Azad
Tony Velkov

Frontiers in Chemistry

doi 10.3389/fchem.2022.843163

5,678 views
14 citations

Original Research

Published on 14 Mar 2022

Label-Free Target Identification Reveals the Anticancer Mechanism of a Rhenium Isonitrile Complex

in Chemical Biology

Junhyeong Yim
Seung Bum Park

Frontiers in Chemistry

doi 10.3389/fchem.2022.850638

2,263 views
4 citations

Mini Review

Published on 10 Mar 2022

Post-Translational Modifications of G Protein–Coupled Receptors Revealed by Proteomics and Structural Biology

in Chemical Biology

Bingjie Zhang
Shanshan Li
Wenqing Shui

Frontiers in Chemistry

doi 10.3389/fchem.2022.843502

7,527 views
15 citations

Original Research

Published on 08 Mar 2022

Electron Transport Lipids Fold Within Membrane-Like Interfaces

in Chemical Biology

Margaret M. Braasch-Turi
Jordan T. Koehn
Kateryna Kostenkova
Cameron Van Cleave
Jacob W. Ives
Heide A. Murakami
Dean C. Crick
Debbie C. Crans

Frontiers in Chemistry

doi 10.3389/fchem.2022.827530

2,416 views
3 citations

Original Research

Published on 07 Mar 2022

Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein

in Chemical Biology

Aneta Kozeleková
Alexandra Náplavová
Tomáš Brom
Norbert Gašparik
Jan Šimek
Josef Houser
Jozef Hritz

Frontiers in Chemistry

doi 10.3389/fchem.2022.835733

7,315 views
15 citations

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Articles

Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening

3D Single Molecule Super-Resolution Microscopy of Whole Nuclear Lamina

Novel Insights Into the Sulfated Glucuronic Acid-Based Anti-SARS-CoV-2 Mechanism of Exopolysaccharides From Halophilic Archaeon Haloarcula hispanica

Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review

Evaluation of Potential DnaK Modulating Proline-Rich Antimicrobial Peptides Identified by Computational Screening

Strategies for Glycoengineering Therapeutic Proteins

Mucin-Type O-Glycosylation Proximal to β-Secretase Cleavage Site Affects APP Processing and Aggregation Fate

The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage

Studying Acetylation of Aconitase Isozymes by Genetic Code Expansion

Genetics Behind the Glycosylation Patterns in the Biosynthesis of Dalbaheptides

Synthesis and Characterization of Phenylboronic Acid-Modified Insulin With Glucose-Dependent Solubility

An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates

Label-Free Target Identification Reveals the Anticancer Mechanism of a Rhenium Isonitrile Complex

Post-Translational Modifications of G Protein–Coupled Receptors Revealed by Proteomics and Structural Biology

Electron Transport Lipids Fold Within Membrane-Like Interfaces

Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein