Frontiers in Cell and Developmental Biology

Original Research

Accepted on 01 Apr 2025

Loss of vitamin D receptor induces premature ovarian insufficiency through compromising the 7-dehydrocholesterol-dependent antiaging effects

Haiyun Chen
Qiuyi Wang
Luxi Shangguan
Zhengquan Zhu
Huan Zhang
Xiang Zou
Qinghe Geng
Yanting Wen
Daojuan Wang
Yong Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1545167

Brief Research Report

Published on 01 Apr 2025

Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities

De Yu Mao
Jordan J. Jesse
Daniel D. Shaye
Jan Kitajewski

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1565262

119 views

Review

Published on 01 Apr 2025

Targeting tumor angiogenesis and metabolism with photodynamic nanomedicine

Yong Lv
Lihui Pu
Bei Ran
Bo Xiang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1558393

148 views

Original Research

Accepted on 31 Mar 2025

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

Cécile Méjécase
Ya Zhou
Nicholas Owen
Pablo Soro-Barrio
Riccardo Cheloni
Neelima Nair
Hajrah Sarkar
Lyes Toualbi
Mariya Moosajee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1511066

105 views

Review

Accepted on 31 Mar 2025

Extracellular vesicles: messengers of cross-talk between gastric cancer cells and the tumor microenvironment

Xiwen Li
Xian Lu
Mi Liu
Junjie Chen
Xirong Lu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1561856

Review

Accepted on 31 Mar 2025

ANXA5: related mechanisms of osteogenesis and additional biological functions

Ming Jin
Jingrun Zhang
Ge Liu
Yimeng Sun
Xiaowei Wei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1553683

Original Research

Accepted on 31 Mar 2025

Genitourinary defects, anxiety and aggressive-like behavior and glucose metabolism disorders in Zmym2 mutant mice with inserted piggyBac transposon

Rufeng Dai
Ye Yin
Minghui Yu
Yumeng Zhang
JingJia Zhang
Tianyi Liu
Xiaoyan Fang
Xiaohui Wu
Qian Shen
Hong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1523266

Original Research

Accepted on 31 Mar 2025

In-vivo and in-vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment

Abdur Rahman Johor
A S M Mahadiuzzaman
Abdulaziz Abdullah Alqusayer
Saleh Abdulaziz Alkarim
F A Dain Md Opo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521809

Mini Review

Accepted on 31 Mar 2025

Primordial Germ Cells as a Potential Model for Understanding (Nutri)epigenetic -Metabolic interactions: A Mini Review

Mariam Ibrahim
Ewa Grochowska
Katarzyna Stadnicka

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1576768

Original Research

Accepted on 31 Mar 2025

Optimizing In Vitro Maturation of Oocytes with Nitric Oxide Microbubble

Lin Qiu
Qi Xu
Yi Lin
Songxue Wang
Huina Zhang
Yi Liu
Junzhao Zhao
Yingzheng Zhao
Haitao Xi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1518226

Original Research

Accepted on 31 Mar 2025

Metabolomic Profiling and Biomarker Identification for Early Detection and Therapeutic Targeting of Doxorubicin-Induced Cardiotoxicity

Jingjing Ding
Xianzhen Feng
Zhongqing Xu
Hong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1543636

Review

Accepted on 31 Mar 2025

Mitochondrial Metabolism Impact on T-cell Dysfunction in Chronic Lymphocytic Leukemia

Wael Gamal
Melanie Mediavilla-Varela
Vishaal Kunta
Dr. Eva Sahakian
Javier Pinilla-Ibarz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577081

126 views

Original Research

Published on 31 Mar 2025

Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-β pathway in lung adenocarcinoma

Honghong Dong
Yahui Tian
Shaowei Xin
Yujie Guo
Suxin Jiang
Zitong Wan
Huaiyu Wang
Yong Han

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1557761

213 views

Review

Published on 31 Mar 2025

Application of human cardiac organoids in cardiovascular disease research

Hongyan Zhang
Peng Qu
Jun Liu
Panke Cheng
Qian Lei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564889

219 views

Review

Published on 31 Mar 2025

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosis

Suqi Liu
Qian Xi
Xuannian Li
Huaman Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1535601

195 views

Original Research

Published on 31 Mar 2025

Doxycycline inhibits MMP-2 retinal activity and modulates the angiogenic process in vitro and in vivo

María Lina Formica
María Constanza Paz
María Victoria Vaglienti
Paula Virginia Subirada
Yamila Fernández
Mariana Belén Joray
José Domingo Luna
Pablo Federico Barcelona
Santiago Daniel Palma
María Cecilia Sánchez

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1561250

243 views

11,900 Publications

Volume 13 - 2025

Loss of vitamin D receptor induces premature ovarian insufficiency through compromising the 7-dehydrocholesterol-dependent antiaging effects

Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities

Targeting tumor angiogenesis and metabolism with photodynamic nanomedicine

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

Extracellular vesicles: messengers of cross-talk between gastric cancer cells and the tumor microenvironment

ANXA5: related mechanisms of osteogenesis and additional biological functions

Genitourinary defects, anxiety and aggressive-like behavior and glucose metabolism disorders in Zmym2 mutant mice with inserted piggyBac transposon

In-vivo and in-vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment

Primordial Germ Cells as a Potential Model for Understanding (Nutri)epigenetic -Metabolic interactions: A Mini Review

Optimizing In Vitro Maturation of Oocytes with Nitric Oxide Microbubble

Metabolomic Profiling and Biomarker Identification for Early Detection and Therapeutic Targeting of Doxorubicin-Induced Cardiotoxicity

Mitochondrial Metabolism Impact on T-cell Dysfunction in Chronic Lymphocytic Leukemia

Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-β pathway in lung adenocarcinoma

Application of human cardiac organoids in cardiovascular disease research

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosis

Doxycycline inhibits MMP-2 retinal activity and modulates the angiogenic process in vitro and in vivo