Frontiers in Cardiovascular Medicine | Cardiovascular Pharmacology and Drug Discovery

Original Research

Accepted on 31 Mar 2025

Mechanism of Ershen Zhenwu Decoction in Ameliorating Chronic Heart Failure via JNK/MAPK-Regulated Apoptosis: Insights from Network Pharmacology and Experimental Validation

in Cardiovascular Pharmacology and Drug Discovery

Yulong Liu
Xinyue Wang
Maomao Zhang
Dan Cheng
Zhenpeng Zhu
Lan Ge
Xiaoyu Cheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1561963

Original Research

Accepted on 27 Mar 2025

Integrating Network Pharmacology and Experimental Validation to Investigate the Mechanism of Gualou Xiebai Banxia Decoction Against Myocardial Ischemia

in Cardiovascular Pharmacology and Drug Discovery

Wanjun Zhu
Ping Shao
Ying Ren
Wenxuan Liu
Xiaorui Han
Kexin Zeng
Chunmei Dai
Feifei Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1512791

Brief Research Report

Published on 14 Mar 2025

Cross-Sectional analysis of demographic and clinical characteristics of patients in the United States using icosapent ethyl

in Cardiovascular Pharmacology and Drug Discovery

Peter P. Toth
John R. Nelson
Handrean Soran
Om P. Ganda
Nathan D. Wong
Hakima Hannachi
David Abrahamson
Josh Hartman
Sierra Luciano
Sephy Philip

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1411233

538 views

Original Research

Published on 20 Feb 2025

A comprehensive study on the impact of Ligustrum vicaryi L. fruit polysaccharide on myocardial fibrosis through animal experiments, network pharmacology and molecular docking

in Cardiovascular Pharmacology and Drug Discovery

Shuling Liu
Meifang Liu
Jianan Wang
Ruixue Rong
Yanwei Gao
Xiaoqi Li
Xin Liu
Shaojian Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1470761

838 views

Original Research

Published on 13 Feb 2025

Network pharmacology to unveil the blood components and mechanisms of Tongmai Yangxin Pills in treating elderly coronary heart disease

in Cardiovascular Pharmacology and Drug Discovery

Yue Zhang
Chao-Hui Li
Yi-Zhi Yan
Jie-Yun Lin
Shan-Shan Zhu
Si-Jie Tan
Peng Zeng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1475546

1,232 views

Systematic Review

Published on 15 Jan 2025

Efficacy and safety of cardiac myosin inhibitors for symptomatic hypertrophic cardiomyopathy: a meta-analysis of randomized controlled trials

in Cardiovascular Pharmacology and Drug Discovery

Anas Abunada
Madiha Shah
Ateesh Kumar
Syeda Lamiya Mir
Dinesh Kumar
Saboor Ahmed
Muhammad Tanzeel
Vikash Kumar
Aashish Meghjiani
Muhammad Basit Ali Siddiqui

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1477487

1,478 views

Review

Published on 15 Jan 2025

Chinese and western medicine treatment of myocardial fibrosis drugs

in Cardiovascular Pharmacology and Drug Discovery

Yuxi Zhu
Fangmei Zhang
Zhongcheng Li
Yu Zhou
Yi Shu
Jian Ruan
Guo Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1477601

1,227 views

Systematic Review

Published on 14 Jan 2025

Comparative efficacy of different drugs in acute heart failure with renal dysfunction: a systematic review and network meta-analysis

in Cardiovascular Pharmacology and Drug Discovery

Qianyu Lv
Qian Wu
Yingtian Yang
Lanlan Li
Xuejiao Ye
Shihan Wang
Yanfei Lv
Manshi Wang
Yushan Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1444068

973 views

Editorial

Published on 07 Jan 2025

Editorial: Novel treatments for cardiovascular diseases by targeting inflammation, oxidative stress, and cell death

in Cardiovascular Pharmacology and Drug Discovery

Dong Fan
Li Wang
Abhijit Chakraborty
Cheng-Lin Zhang
Feng Hua Yang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1538222

769 views

Original Research

Published on 06 Jan 2025

Effects of different doses of remimazolam on the quality of sedation and cardiac function in elderly patients: a double-blind randomised controlled study

in Cardiovascular Pharmacology and Drug Discovery

Liu Minghong
Qizhu Feng
Huichun Chen
Ju Li
Jun Shi

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1453608

866 views

Review

Published on 03 Dec 2024

Traditional Chinese medicine for cardiovascular disease: efficacy and safety

in Cardiovascular Pharmacology and Drug Discovery

Youwei Lin
Yuanshan Han
Yuhong Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1419169

1,427 views

Systematic Review

Published on 22 Nov 2024

Exploring research trends and hotspots on PCSK9 inhibitor studies: a bibliometric and visual analysis spanning 2007 to 2023

in Cardiovascular Pharmacology and Drug Discovery

Ping Lai
Shuquan Xu
Ziyou Liu
Jiayuan Ling
Kejun Tian
Jianwei Yan
Dong Chen
Yiming Zhong
Jinhua Xue

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1474472

1,747 views

Original Research

Published on 29 Oct 2024

Metabolomics revealed pharmacodynamic effects of aspirin and indobufen in patients after percutaneous transluminal angioplasty surgery

in Cardiovascular Pharmacology and Drug Discovery

Shaobo Sun
Kang Xun
Damei Li
Renjie Bao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1433643

674 views

Original Research

Published on 24 Oct 2024

Simultaneous determination of the combined and free concentrations of atorvastatin and its major metabolite in vitro and in vivo based on ultraﬁltration coupled with UPLC-MS/MS method: an application in a protein binding rate and metabolism ability study in uremic hemodialysis patients

in Cardiovascular Pharmacology and Drug Discovery

Ming-Chen Cao
Xin Huang
Bo-Hao Tang
Hai-Yan Shi
Yi Zheng
Wei Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1461181

881 views

Review

Published on 18 Oct 2024

Research progress of sea buckthorn (Hippophae rhamnoides L.) in prevention and treatment of cardiovascular disease

in Cardiovascular Pharmacology and Drug Discovery

Yumeng Chen
Weiwei He
Hanjing Cao
Zhenzhen Wang
Jiping Liu
Bin Wang
Chuan Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1477636

2,961 views

Systematic Review

Published on 25 Sep 2024

The efficacy and safety of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors combined with statins in patients with hypercholesterolemia: a network meta-analysis

in Cardiovascular Pharmacology and Drug Discovery

Dong Liu
Jin Zhang
Xiaoyu Zhang
Fengli Jiang
Yiping Wu
Beibei Yang
Xinghuan Li
Xiongxiong Fan
Han Li
Yu Sun

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1454918

2,602 views