Original Research

Published on 11 Nov 2024

Non-invasive real-time investigation of colorectal cells tight junctions by Raman microspectroscopy analysis combined with machine learning algorithms for organ-on-chip applications

in Organoids and Organ-On-A-Chip

A. Calogiuri
D. Bellisario
E. Sciurti
L. Blasi
V. Esposito
F. Casino
P. Siciliano
L. Francioso

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1458404

280 views

Original Research

Published on 08 Oct 2024

Assessing the metastatic potential of circulating tumor cells using an organ-on-chip model

in Organoids and Organ-On-A-Chip

Karin F. Schmid
Soheila Zeinali
Susanne K. Moser
Christelle Dubey
Sabine Schneider
Haibin Deng
Simon Haefliger
Thomas M. Marti
Olivier T. Guenat

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1457884

998 views

Original Research

Published on 02 Oct 2024

A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34+ hematopoietic cells while allowing the detection of tumorigenic expansion

in Organoids and Organ-On-A-Chip

Paolo Ritter
Stefania Oliveto
Chiara Cordiglieri
Alessandra Fasciani
Christian Andrea Di Buduo
Lucrezia della Volpe
Alberto Bocconi
Claudio Conci
Carolina Paula Miguel
Raffaella Di Micco

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1388312

838 views

Review

Published on 02 Oct 2024

Tumor-on-chip platforms for breast cancer continuum concept modeling

in Organoids and Organ-On-A-Chip

Anca-Narcisa Neagu
Danielle Whitham
Pathea Bruno
Nicholas Versaci
Peter Biggers
Costel C. Darie

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1436393

871 views

Review

Published on 25 Sep 2024

Improving tumor microenvironment assessment in chip systems through next-generation technology integration

in Organoids and Organ-On-A-Chip

Daniela Gaebler
Stephanie J. Hachey
Christopher C. W. Hughes

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1462293

1,006 views

Editorial

Published on 25 Sep 2024

Editorial: Emerging bioanalytical techniques and therapies for human disease models

in Organoids and Organ-On-A-Chip

Xuerui Wang
Jinnuo Lu
Yixiao Huang
Xinhao Liu
Guocheng Fang
Chih-Tsung Yang
Zhaobin Guo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1453813

420 views

Original Research

Published on 06 Sep 2024

Bidirectionally validated in silico and in vitro formation of specific depth zone-derived chondrocyte spheroids and clusters

in Organoids and Organ-On-A-Chip

Eiichiro Takada
Hayato L. Mizuno
Yoshiki Takeoka
Shuichi Mizuno

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1440434

857 views

Original Research

Published on 02 Aug 2024

A multiparametric analysis including single-cell and subcellular feature assessment reveals differential behavior of spheroid cultures on distinct ultra-low attachment plate types

in Organoids and Organ-On-A-Chip

Mario Vitacolonna
Roman Bruch
Ane Agaçi
Elina Nürnberg
Tiziana Cesetti
Florian Keller
Francesco Padovani
Simeon Sauer
Kurt M. Schmoller
Markus Reischl

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1422235

1,719 views

Original Research

Published on 25 Jun 2024

Optimization and validation of a fat-on-a-chip model for non-invasive therapeutic drug discovery

in Organoids and Organ-On-A-Chip

Lindsey K. Huff
Charles M. Amurgis
Lauren E. Kokai
Rosalyn D. Abbott

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1404327

1,343 views

Original Research

Published on 12 Jun 2024

Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling

in Organoids and Organ-On-A-Chip

Chencheng Wang
Shadab Abadpour
Aleksandra Aizenshtadt
Andrea Dalmao-Fernandez
Merete Høyem
Ingrid Wilhelmsen
Justyna Stokowiec
Petter Angell Olsen
Stefan Krauss
Simona Chera

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1392575

1,596 views

Review

Published on 24 May 2024

Progress and application of lung-on-a-chip for lung cancer

in Organoids and Organ-On-A-Chip

Lantao Li
Wentao Bo
Guangyan Wang
Xin Juan
Haiyi Xue
Hongwei Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1378299

1,954 views
2 citations

Original Research

Published on 12 Apr 2024

In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus

in Organoids and Organ-On-A-Chip

Hao Wang
Raehyun Kim
Yuli Wang
Kathleen L. Furtado
Christopher E. Sims
Rita Tamayo
Nancy L. Allbritton

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1382389

1,309 views
1 citation

Original Research

Published on 04 Apr 2024

Rational design of a near-infrared fluorescent probe for monitoring butyrylcholinesterase activity and its application in development of inhibitors

in Organoids and Organ-On-A-Chip

Hao Li
Xiao-Dong Li
Chao-Hua Yan
Zhen-Hua Ni
Mu-Han Lü
Li-Wei Zou
Ling Yang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1387146

1,307 views
1 citation

Original Research

Published on 03 Apr 2024

Single molecule studies of dynamic platelet interactions with endothelial cells

in Organoids and Organ-On-A-Chip

Fabian Hauser
Christoph Naderer
Eleni Priglinger
Anja Peterbauer
Michael B. Fischer
Heinz Redl
Jaroslaw Jacak

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1372807

1,590 views

Review

Published on 28 Mar 2024

Revolutionizing nephrology research: expanding horizons with kidney-on-a-chip and beyond

in Organoids and Organ-On-A-Chip

Wei Huang
Yi-Yuan Chen
Fang-Fang He
Chun Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1373386

2,902 views
2 citations

Original Research

Published on 18 Mar 2024

Evaluation of nanoparticle albumin-bound paclitaxel loaded macrophages for glioblastoma treatment based on a microfluidic chip

in Organoids and Organ-On-A-Chip

Zuorun Xie
Junyi Ye
Xinghua Gao
Hang Chen
Maosong Chen
Jiangfang Lian
Jingyun Ma
Hongcai Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1361682

1,871 views
1 citation

Navigation group

Articles

Non-invasive real-time investigation of colorectal cells tight junctions by Raman microspectroscopy analysis combined with machine learning algorithms for organ-on-chip applications

Assessing the metastatic potential of circulating tumor cells using an organ-on-chip model

A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34+ hematopoietic cells while allowing the detection of tumorigenic expansion

Tumor-on-chip platforms for breast cancer continuum concept modeling

Improving tumor microenvironment assessment in chip systems through next-generation technology integration

Editorial: Emerging bioanalytical techniques and therapies for human disease models

Bidirectionally validated in silico and in vitro formation of specific depth zone-derived chondrocyte spheroids and clusters

A multiparametric analysis including single-cell and subcellular feature assessment reveals differential behavior of spheroid cultures on distinct ultra-low attachment plate types

Optimization and validation of a fat-on-a-chip model for non-invasive therapeutic drug discovery

Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling

Progress and application of lung-on-a-chip for lung cancer

In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus

Rational design of a near-infrared fluorescent probe for monitoring butyrylcholinesterase activity and its application in development of inhibitors

Single molecule studies of dynamic platelet interactions with endothelial cells

Revolutionizing nephrology research: expanding horizons with kidney-on-a-chip and beyond

Evaluation of nanoparticle albumin-bound paclitaxel loaded macrophages for glioblastoma treatment based on a microfluidic chip