Original Research

Published on 01 Aug 2014

The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

in Cellular and Molecular Mechanisms of Brain-aging

Yun-Ching Chang
Wei-Chao Chang
Kuo-Hsuan Hung
Der-Ming Yang
Yung-Hsin Cheng
Yi-Wen Liao
Lin-Chung Woung
Ching-Yao Tsai
Chih-Chien Hsu
Tai-Chi Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00191

15,023 views
74 citations

Review

Published on 23 Jul 2014

The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

David B. Lovejoy
Gilles J. Guillemin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00173

10,820 views
56 citations

Review

Published on 21 Jul 2014

β-secretase inhibitor; a promising novel therapeutic drug in Alzheimer’s disease

in Cellular and Molecular Mechanisms of Brain-aging

Kelly Willemijn Menting
Jurgen A. H. R. Claassen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00165

26,955 views
127 citations

Review

Published on 03 Jul 2014

Copper: from neurotransmission to neuroproteostasis

in Cellular and Molecular Mechanisms of Brain-aging

Carlos M. Opazo
Mark A. Greenough
Ashley I. Bush

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00143

22,364 views
127 citations

Original Research

Published on 03 Jul 2014

Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

in Cellular and Molecular Mechanisms of Brain-aging

Johan Holmberg
Azra Alajbegovic
Kinga Izabela Gawlik
Linda Elowsson
Madeleine Durbeej

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00155

5,485 views
24 citations

Review

Published on 25 Jun 2014

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

in Cellular and Molecular Mechanisms of Brain-aging

Sara M. Hancock
David I. Finkelstein
Paul A. Adlard

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00137

8,485 views
37 citations

Original Research

Published on 20 Jun 2014

Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

in Cellular and Molecular Mechanisms of Brain-aging

George E. Barreto
Maria Santos-Galindo
Luis Miguel Garcia-Segura

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00132

9,565 views
63 citations

Original Research

Published on 19 Jun 2014

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system

in Cellular and Molecular Mechanisms of Brain-aging

Josée Coulombe
Prasanna Gamage
Madison T. Gray
Mei Zhang
Matthew Y. Tang
John Woulfe
M. Jill Saffrey
Douglas A. Gray

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00129

8,860 views
36 citations

Original Research

Published on 16 Jun 2014

Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

in Cellular and Molecular Mechanisms of Brain-aging

Megan W. Bourassa
Hilda H. Brown
David R. Borchelt
Stefan Vogt
Lisa M. Miller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00110

8,940 views
54 citations

Original Research

Published on 03 Jun 2014

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin

in Cellular and Molecular Mechanisms of Brain-aging

Huiqiang Chen
Xianbao Liu
Wei Zhu
Han Chen
Xinyang Hu
Zhi Jiang
Yinchuan Xu
Lihan Wang
Yu Zhou
Panpan Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00103

13,861 views
98 citations

Review

Published on 22 May 2014

Degeneration of Neuromuscular Junction in Age and Dystrophy

in Cellular and Molecular Mechanisms of Brain-aging

Rüdiger Rudolf
Muzamil Majid Khan
Siegfried Labeit
Michael R. Deschenes

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00099

21,021 views
151 citations

Original Research

Published on 16 May 2014

Alzheimer’s disease causation by copper toxicity and treatment with zinc

in Cellular and Molecular Mechanisms of Brain-aging

George J. Brewer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00092

32,973 views
58 citations

Mini Review

Published on 14 May 2014

Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition

in Cellular and Molecular Mechanisms of Brain-aging

Alberto Granzotto
Paolo Zatta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00095

37,452 views
89 citations

Original Research

Published on 13 May 2014

Myogenic Potential of Canine Craniofacial Satellite Cells

in Cellular and Molecular Mechanisms of Brain-aging

Rita Maria Laura La Rovere
Mattia Quattrocelli
Tiziana Pietrangelo
Ester Sara Di Filippo
Lisa Maccatrozzo
Marco Cassano
Francesco Mascarello
Inès Barthélémy
Stephane Blot
Maurilio Sampaolesi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00090

7,194 views
22 citations

Original Research

Published on 07 May 2014

Glutamatergic signaling and low prodynorphin expression are associated with intact memory and reduced anxiety in rat models of healthy aging

in Cellular and Molecular Mechanisms of Brain-aging

Caroline Ménard
Rémi Quirion
Sylvain Bouchard
Guylaine Ferland
Pierrette Gaudreau

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00081

6,190 views
24 citations

Original Research

Published on 21 Apr 2014

Age-related neurochemical changes in the rhesus macaque inferior colliculus

in Cellular and Molecular Mechanisms of Brain-aging

James R. Engle
Daniel T. Gray
Heather Turner
Julia B. Udell
Gregg H. Recanzone

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00073

4,968 views
32 citations

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Articles

The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

β-secretase inhibitor; a promising novel therapeutic drug in Alzheimer’s disease

Copper: from neurotransmission to neuroproteostasis

Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system

Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin

Degeneration of Neuromuscular Junction in Age and Dystrophy

Alzheimer’s disease causation by copper toxicity and treatment with zinc

Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition

Myogenic Potential of Canine Craniofacial Satellite Cells

Glutamatergic signaling and low prodynorphin expression are associated with intact memory and reduced anxiety in rat models of healthy aging

Age-related neurochemical changes in the rhesus macaque inferior colliculus