Mini Review

Published on 06 Dec 2019

Perturbations of Ubiquitin-Proteasome-Mediated Proteolysis in Aging and Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Ashok N. Hegde
Spencer G. Smith
Lindsey M. Duke
Allison Pourquoi
Savannah Vaz

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00324

10,623 views
59 citations

Original Research

Published on 21 Nov 2019

Role of Tau Protein in Remodeling of Circadian Neuronal Circuits and Sleep

in Cellular and Molecular Mechanisms of Brain-aging

Mercedes Arnes
Maria E. Alaniz
Caline S. Karam
Joshua D. Cho
Gonzalo Lopez
Jonathan A. Javitch
Ismael Santa-Maria

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00320

8,514 views
22 citations

Original Research

Published on 20 Nov 2019

Enhanced Tau Protein Translation by Hyper-Excitation

in Cellular and Molecular Mechanisms of Brain-aging

Shunsuke Kobayashi
Toru Tanaka
Yoshiyuki Soeda
Akihiko Takashima

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00322

4,659 views
22 citations

Original Research

Published on 19 Nov 2019

Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice

in Cellular and Molecular Mechanisms of Brain-aging

Yinghua Liu
Wei Wei
Narjes Baazaoui
Fei Liu
Khalid Iqbal

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00309

5,154 views
10 citations

Review

Published on 12 Nov 2019

SIRT3 Regulation of Mitochondrial Quality Control in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Hao Meng
Wan-Yu Yan
Yu-Hong Lei
Zheng Wan
Ye-Ye Hou
Lian-Kun Sun
Jue-Pu Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00313

13,578 views
88 citations

Original Research

Published on 23 Oct 2019

Proteome Profiling of Cerebral Vessels in Rhesus Macaques: Dysregulation of Antioxidant Activity and Extracellular Matrix Proteins Contributes to Cerebrovascular Aging in Rhesus Macaques

in Cellular and Molecular Mechanisms of Brain-aging

Xia Wang
Yifan Liu
Yangjie Jia
Haotian Liu
Xinjie Bao
Zhanlong He
Wei Ge

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00293

3,311 views
9 citations

Original Research

Published on 24 Sep 2019

Attenuating Cholinergic Transmission Increases the Number of Satellite Cells and Preserves Muscle Mass in Old Age

in Cellular and Molecular Mechanisms of Brain-aging

Sydney K. Vaughan
Natalia M. Sutherland
Gregorio Valdez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00262

5,225 views
10 citations

Original Research

Published on 13 Sep 2019

Age and Ketogenic Diet Have Dissociable Effects on Synapse-Related Gene Expression Between Hippocampal Subregions

in Cellular and Molecular Mechanisms of Brain-aging

Abbi R. Hernandez
Caesar M. Hernandez
Leah M. Truckenbrod
Keila T. Campos
Joseph A. McQuail
Jennifer L. Bizon
Sara N. Burke

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00239

7,009 views
18 citations

Original Research

Published on 12 Sep 2019

In vivo Bioluminescence Imaging Used to Monitor Disease Activity and Therapeutic Response in a Mouse Model of Tauopathy

in Cellular and Molecular Mechanisms of Brain-aging

Ambrose A. Dunn-Meynell
Peter Dowling
Michelle Marchese
Esther Rodriguez
Benjamin Blumberg
Yun-Beom Choi
Deeya Gaindh
Wei Lu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00252

4,565 views
9 citations

Original Research

Published on 12 Sep 2019

A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+

in Cellular and Molecular Mechanisms of Brain-aging

Ross Grant
Jade Berg
Richard Mestayer
Nady Braidy
James Bennett
Susan Broom
James Watson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00257

63,064 views
33 citations

Brief Research Report

Published on 04 Sep 2019

Memory Decline and Behavioral Inflexibility in Aged Mice Are Correlated With Dysregulation of Protein Synthesis Capacity

in Cellular and Molecular Mechanisms of Brain-aging

Wenzhong Yang
Xueyan Zhou
Tao Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00246

7,543 views
36 citations

Original Research

Published on 04 Sep 2019

Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway

in Cellular and Molecular Mechanisms of Brain-aging

Cuilin Zhang
Zhenqiu Tan
Yongzhuang Xie
Yingjun Zhao
Timothy Y. Huang
Zhaoping Lu
Hong Luo
Dan Can
Huaxi Xu
Yun-wu Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00243

4,199 views
9 citations

Brief Research Report

Published on 30 Aug 2019

Novel Functions of the Neurodegenerative-Related Gene Tau in Cancer

in Cellular and Molecular Mechanisms of Brain-aging

Ricardo Gargini
Berta Segura-Collar
Pilar Sánchez-Gómez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00231

8,019 views
52 citations

Review

Published on 28 Aug 2019

Exosome Determinants of Physiological Aging and Age-Related Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Marianna D’Anca
Chiara Fenoglio
Maria Serpente
Beatrice Arosio
Matteo Cesari
Elio Angelo Scarpini
Daniela Galimberti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00232

19,775 views
128 citations

Original Research

Published on 27 Aug 2019

Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay

in Cellular and Molecular Mechanisms of Brain-aging

Aimi Syamima Abdul Manap
Amelia Cheng Wei Tan
Weng Hhin Leong
Adeline Yoke Yin Chia
Shantini Vijayabalan
Aditya Arya
Eng Hwa Wong
Farzana Rizwan
Umesh Bindal
Shajan Koshy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00206

16,766 views
68 citations

Original Research

Published on 31 Jul 2019

Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task

in Cellular and Molecular Mechanisms of Brain-aging

Jana Lubec
Roman Smidak
Jovana Malikovic
Daniel Daba Feyissa
Volker Korz
Harald Höger
Gert Lubec

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00198

4,260 views
21 citations

Navigation group

Articles

Perturbations of Ubiquitin-Proteasome-Mediated Proteolysis in Aging and Alzheimer’s Disease

Role of Tau Protein in Remodeling of Circadian Neuronal Circuits and Sleep

Enhanced Tau Protein Translation by Hyper-Excitation

Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice

SIRT3 Regulation of Mitochondrial Quality Control in Neurodegenerative Diseases

Proteome Profiling of Cerebral Vessels in Rhesus Macaques: Dysregulation of Antioxidant Activity and Extracellular Matrix Proteins Contributes to Cerebrovascular Aging in Rhesus Macaques

Attenuating Cholinergic Transmission Increases the Number of Satellite Cells and Preserves Muscle Mass in Old Age

Age and Ketogenic Diet Have Dissociable Effects on Synapse-Related Gene Expression Between Hippocampal Subregions

In vivo Bioluminescence Imaging Used to Monitor Disease Activity and Therapeutic Response in a Mouse Model of Tauopathy

A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+

Memory Decline and Behavioral Inflexibility in Aged Mice Are Correlated With Dysregulation of Protein Synthesis Capacity

Appoptosin Mediates Lesions Induced by Oxidative Stress Through the JNK-FoxO1 Pathway

Novel Functions of the Neurodegenerative-Related Gene Tau in Cancer

Exosome Determinants of Physiological Aging and Age-Related Neurodegenerative Diseases

Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay

Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task