Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 18 Aug 2020

DNA Methylation Manipulation of Memory Genes Is Involved in Sevoflurane Induced Cognitive Impairments in Aged Rats

in Cellular and Molecular Mechanisms of Brain-aging

Cheng Ni
Min Qian
Jiao Geng
Yinyin Qu
Yi Tian
Ning Yang
Shuai Li
Hui Zheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00211

5,111 views
13 citations

Original Research

Published on 14 Aug 2020

Ultra-High-Resolution in vitro MRI Study of Age-Related Brain Subcortical Susceptibility Alteration in Rhesus Monkeys at 9.4 T

in Cellular and Molecular Mechanisms of Brain-aging

Qingqing Wen
Hongyi Yang
Jiali Li
Jin Zhang
Haiyang Tong
Qiong Ye
Kai Zhong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00259

2,644 views
5 citations

Review

Published on 06 Aug 2020

Stem Cells of the Aging Brain

in Cellular and Molecular Mechanisms of Brain-aging

Alexandra M. Nicaise
Cory M. Willis
Stephen J. Crocker
Stefano Pluchino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00247

18,320 views
65 citations

Review

Published on 21 Jul 2020

A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Riccardo Cristofani
Valeria Crippa
Maria Elena Cicardi
Barbara Tedesco
Veronica Ferrari
Marta Chierichetti
Elena Casarotto
Margherita Piccolella
Elio Messi
Mariarita Galbiati

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00191

7,479 views
17 citations

Original Research

Published on 16 Jul 2020

Memory and Learning Deficits Are Associated With Ca2+ Dyshomeostasis in Normal Aging

in Cellular and Molecular Mechanisms of Brain-aging

Arkady Uryash
Valentina Flores
Jose A. Adams
Paul D. Allen
Jose R. Lopez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00224

9,921 views
30 citations

Original Research

Published on 14 Jul 2020

A Nationwide Survey and Multicenter Registry-Based Database of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy in Japan

in Cellular and Molecular Mechanisms of Brain-aging

Akihiro Shindo
Ken-ichi Tabei
Akira Taniguchi
Hiroaki Nozaki
Osamu Onodera
Akihiko Ueda
Yukio Ando
Takao Urabe
Kazumi Kimura
Kazuo Kitagawa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00216

9,144 views
17 citations

Original Research

Published on 10 Jul 2020

COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging via the BDNF/ERK1/2 Signaling Pathway

in Cellular and Molecular Mechanisms of Brain-aging

Yan-Bin Xiyang
Ruan Liu
Xu-Yang Wang
Shan Li
Ya Zhao
Bing-Tuan Lu
Zhi-Cheng Xiao
Lian-Feng Zhang
Ting-Hua Wang
Jie Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00215

5,862 views
27 citations

Original Research

Published on 06 Jul 2020

Effects of Prenatal Exposure to Inflammation Coupled With Stress Exposure During Adolescence on Cognition and Synaptic Protein Levels in Aged CD-1 Mice

in Cellular and Molecular Mechanisms of Brain-aging

Zhe-Zhe Zhang
Zhan-Qiang Zhuang
Shi-Yu Sun
He-Hua Ge
Yong-Fang Wu
Lei Cao
Lan Xia
Qi-Gang Yang
Fang Wang
Gui-Hai Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00157

3,789 views
11 citations

Mini Review

Published on 09 Jun 2020

Extracellular HIV-1 Tat Mediates Increased Glutamate in the CNS Leading to Onset of Senescence and Progression of HAND

in Cellular and Molecular Mechanisms of Brain-aging

Jamie Marino
Brian Wigdahl
Michael R. Nonnemacher

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00168

4,228 views
35 citations

Brief Research Report

Published on 09 Jun 2020

Age-Dependent Heterogeneity of Murine Olfactory Bulb Astrocytes

in Cellular and Molecular Mechanisms of Brain-aging

Marcel Klein
Christian Lohr
Damian Droste

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00172

6,826 views
16 citations

Original Research

Published on 04 Jun 2020

TDP-43 Is Elevated in Plasma Neuronal-Derived Exosomes of Patients With Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Nan Zhang
Dongmei Gu
Meng Meng
Marc L. Gordon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00166

7,167 views
32 citations

Brief Research Report

Published on 03 Jun 2020

Excessive Production of Transforming Growth Factor β1 Causes Mural Cell Depletion From Cerebral Small Vessels

in Cellular and Molecular Mechanisms of Brain-aging

Taisuke Kato
Yumi Sekine
Hiroaki Nozaki
Masahiro Uemura
Shoichiro Ando
Sachiko Hirokawa
Osamu Onodera

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00151

4,486 views
18 citations

Original Research

Published on 12 May 2020

Exploration of the Molecular Mechanism for Lipoprotein Lipase Expression Variations in SH-SY5Y Cells Exposed to Different Doses of Amyloid-Beta Protein

in Cellular and Molecular Mechanisms of Brain-aging

Jingzhu Zhang
Yufan Liu
Sihui Wang
Ran Que
Weidong Zhao
Li An

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00132

3,112 views
2 citations

Original Research

Published on 07 May 2020

Gender Differences in Neurodegeneration, Neuroinflammation and Na+-Ca2+ Exchangers in the Female A53T Transgenic Mouse Model of Parkinson’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Giulia Costa
Maria Jose Sisalli
Nicola Simola
Salvatore Della Notte
Maria Antonietta Casu
Marcello Serra
Annalisa Pinna
Antonio Feliciello
Lucio Annunziato
Antonella Scorziello

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00118

6,641 views
20 citations

Original Research

Published on 07 May 2020

Genome-Wide Screen of the Hippocampus in Aged Rats Identifies Mitochondria, Metabolism and Aging Processes Implicated in Sevoflurane Anesthesia

in Cellular and Molecular Mechanisms of Brain-aging

Yujie Wang
Min Qian
Yinyin Qu
Ning Yang
Bing Mu
Kaixi Liu
Jing Yang
Yang Zhou
Cheng Ni
Jing Zhong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00122

6,443 views
17 citations

Original Research

Published on 29 Apr 2020

Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo

in Cellular and Molecular Mechanisms of Brain-aging

Amy R. Nelson
Meghana A. Sagare
Yaoming Wang
Kassandra Kisler
Zhen Zhao
Berislav V. Zlokovic

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00108

9,002 views
72 citations