Original Research

Published on 08 Jan 2021

Striatal Transcriptome Reveals Differences Between Cognitively Impaired and Unimpaired Aged Male Rats

in Cellular and Molecular Mechanisms of Brain-aging

Volker Korz
Christopher Kremslehner
Jovana Maliković
Ahmed Hussein
Daniel Daba Feyissa
Ionela-Mariana Nagelreiter
Roman Smidak
Roberto Plasenzotti
Florian Gruber
Gert Lubec

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.611572

3,929 views
2 citations

Original Research

Published on 17 Dec 2020

Age-Dependent Activation and Neuronal Differentiation of Lgr5+ Basal Cells in Injured Olfactory Epithelium via Notch Signaling Pathway

in Cellular and Molecular Mechanisms of Brain-aging

Xuewen Li
Meimei Tong
Li Wang
Yumei Qin
Hongmeng Yu
Yiqun Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.602688

4,704 views
5 citations

Original Research

Published on 16 Dec 2020

Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

in Cellular and Molecular Mechanisms of Brain-aging

Bernard Cuenoud
Özlem Ipek
Maya Shevlyakova
Maurice Beaumont
Stephen C. Cunnane
Rolf Gruetter
Lijing Xin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.609517

16,522 views
32 citations

Original Research

Published on 16 Dec 2020

Senescent Cell-Secreted Netrin-1 Modulates Aging-Related Disorders by Recruiting Sympathetic Fibers

in Cellular and Molecular Mechanisms of Brain-aging

Ai Qing Yu
Jie Wang
Xiao Jia Zhou
Ke Yu Chen
You De Cao
Zhi Xiao Wang
Ze Bin Mao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.507140

5,920 views
7 citations

Systematic Review

Published on 10 Dec 2020

AChRs Degeneration at NMJ in Aging-Associated Sarcopenia–A Systematic Review

in Cellular and Molecular Mechanisms of Brain-aging

Zhengyuan Bao
Can Cui
Simon Kwoon-Ho Chow
Ling Qin
Ronald Man Yeung Wong
Wing-Hoi Cheung

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.597811

9,075 views
26 citations

Mini Review

Published on 10 Dec 2020

Mitochondrial Dynamics and Bioenergetic Alteration During Inflammatory Activation of Astrocytes

in Cellular and Molecular Mechanisms of Brain-aging

Md Habibur Rahman
Kyoungho Suk

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.614410

5,310 views
15 citations

Original Research

Published on 03 Dec 2020

Deficiency of Mitochondrial Functions and Peroxidation of Frontoparietal Cortex Enhance Isoflurane Sensitivity in Aging Mice

in Cellular and Molecular Mechanisms of Brain-aging

Cansheng Gong
Donghang Zhang
Wei Ou
Mengchan Ou
Peng Liang
Daqing Liao
Weiyi Zhang
Tao Zhu
Jin Liu
Cheng Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.583542

2,883 views
1 citation

Review

Published on 02 Dec 2020

γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors

in Cellular and Molecular Mechanisms of Brain-aging

Eitan Wong
Georgia R. Frost
Yue-Ming Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.614690

5,730 views
16 citations

Editorial

Published on 26 Nov 2020

Editorial: Proteomics as a Tool for Biomarker and Drug Target Discovery: Improving the Diagnosis and Treatment of Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Olivia Belbin
Sylvain Lehmann
Eduard Sabidó
Christophe Hirtz

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00232

2,791 views
1 citation

Review

Published on 24 Nov 2020

Resveratrol Modulates the Gut-Brain Axis: Focus on Glucagon-Like Peptide-1, 5-HT, and Gut Microbiota

in Cellular and Molecular Mechanisms of Brain-aging

Ji Yeon Chung
Jae-Ho Jeong
Juhyun Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.588044

10,665 views
30 citations

Original Research

Published on 24 Nov 2020

LncRNA-T199678 Mitigates α-Synuclein-Induced Dopaminergic Neuron Injury via miR-101-3p

in Cellular and Molecular Mechanisms of Brain-aging

Lu-Lu Bu
Ying-Yu Xie
Dan-Yu Lin
Ying Chen
Xiu-Na Jing
Yan-Ran Liang
Su-Dan Peng
Kai-Xun Huang
En-Xiang Tao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.599246

3,678 views
27 citations

Perspective

Published on 23 Nov 2020

Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recent Brazilian Environmental Disasters?

in Cellular and Molecular Mechanisms of Brain-aging

Ramon da Silva Raposo
Daniel Vieira Pinto
Ricardo Moreira
Ronaldo Pereira Dias
Carlos Alberto Fontes Ribeiro
Reinaldo Barreto Oriá
João Oliveira Malva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.591601

6,137 views
20 citations

Original Research

Published on 23 Nov 2020

Alpha-Synuclein Accumulation and Its Phosphorylation in the Enteric Nervous System of Patients Without Neurodegeneration: An Explorative Study

in Cellular and Molecular Mechanisms of Brain-aging

Lu-Lu Bu
Kai-Xun Huang
De-Zhi Zheng
Dan-Yu Lin
Ying Chen
Xiu-Na Jing
Yan-Ran Liang
En-Xiang Tao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.575481

4,823 views
17 citations

Original Research

Published on 16 Nov 2020

1% Isoflurane and 1.2 μg/ml of Propofol: A Combination of Anesthetics That Causes the Least Damage to Hypoxic Neurons

in Cellular and Molecular Mechanisms of Brain-aging

Xinyue Bu
Tang Li
Di Guo
Chenyi Yang
Jinxin Wang
Xinyi Wang
Zhuo Yang
Haiyun Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.591938

2,738 views
3 citations

Original Research

Published on 12 Nov 2020

Longitudinal Characterization of Transcriptomic, Functional, and Morphological Features in Human iPSC-Derived Neurons and Their Application to Investigate Translational Progranulin Disease Biology

in Cellular and Molecular Mechanisms of Brain-aging

Gaëlle Robin
J. Corey Evans
David N. Hauser
Paul Wren
Andreas Zembrzycki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.576678

7,235 views
4 citations

Original Research

Published on 10 Nov 2020

Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Arpita Konar
Rajkumar Singh Kalra
Anupama Chaudhary
Aashika Nayak
Kanive P. Guruprasad
Kapaettu Satyamoorthy
Yoshiyuki Ishida
Keiji Terao
Sunil C. Kaul
Renu Wadhwa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.561925

6,084 views
13 citations

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Articles

Striatal Transcriptome Reveals Differences Between Cognitively Impaired and Unimpaired Aged Male Rats

Age-Dependent Activation and Neuronal Differentiation of Lgr5+ Basal Cells in Injured Olfactory Epithelium via Notch Signaling Pathway

Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

Senescent Cell-Secreted Netrin-1 Modulates Aging-Related Disorders by Recruiting Sympathetic Fibers

AChRs Degeneration at NMJ in Aging-Associated Sarcopenia–A Systematic Review

Mitochondrial Dynamics and Bioenergetic Alteration During Inflammatory Activation of Astrocytes

Deficiency of Mitochondrial Functions and Peroxidation of Frontoparietal Cortex Enhance Isoflurane Sensitivity in Aging Mice

γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors

Editorial: Proteomics as a Tool for Biomarker and Drug Target Discovery: Improving the Diagnosis and Treatment of Neurodegenerative Diseases

Resveratrol Modulates the Gut-Brain Axis: Focus on Glucagon-Like Peptide-1, 5-HT, and Gut Microbiota

LncRNA-T199678 Mitigates α-Synuclein-Induced Dopaminergic Neuron Injury via miR-101-3p

Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recent Brazilian Environmental Disasters?

Alpha-Synuclein Accumulation and Its Phosphorylation in the Enteric Nervous System of Patients Without Neurodegeneration: An Explorative Study

1% Isoflurane and 1.2 μg/ml of Propofol: A Combination of Anesthetics That Causes the Least Damage to Hypoxic Neurons

Longitudinal Characterization of Transcriptomic, Functional, and Morphological Features in Human iPSC-Derived Neurons and Their Application to Investigate Translational Progranulin Disease Biology

Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases