Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 25 May 2021

Cornel Iridoid Glycoside Protects Against STAT1-Dependent Synapse and Memory Deficits by Increasing N-Methyl-D-aspartate Receptor Expression in a Tau Transgenic Mice

in Cellular and Molecular Mechanisms of Brain-aging

Denglei Ma
Rui Huang
Kaiwen Guo
Zirun Zhao
Weipeng Wei
Lihong Gu
Lin Li
Lan Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.671206

3,440 views
9 citations

Original Research

Published on 21 May 2021

Notch3-Dependent Effects on Adult Neurogenesis and Hippocampus-Dependent Learning in a Modified Transgenic Model of CADASIL

in Cellular and Molecular Mechanisms of Brain-aging

Fanny Ehret
Ricardo Moreno Traspas
Marie-Theres Neumuth
Bianca Hamann
Daniela Lasse
Gerd Kempermann

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.617733

4,082 views
7 citations

Original Research

Published on 19 May 2021

Integrative Analysis of lncRNA and mRNA and Profiles in Postoperative Delirium Patients

in Cellular and Molecular Mechanisms of Brain-aging

Yuxiang Song
Xiaoyan Wang
Aisheng Hou
Hao Li
Jingsheng Lou
Yanhong Liu
Jiangbei Cao
Weidong Mi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.665935

5,161 views
9 citations

Original Research

Published on 19 May 2021

Circular RNA circDUS2 Is a Potential Biomarker for Intracranial Aneurysm

in Cellular and Molecular Mechanisms of Brain-aging

Xin Chen
Shuzhe Yang
Junhua Yang
Qingyuan Liu
Maogui Li
Jun Wu
Hao Wang
Shuo Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.632448

3,992 views
12 citations

Editorial

Published on 17 May 2021

Editorial: Stem Cells and Aging

in Cellular and Molecular Mechanisms of Brain-aging

Cesar V. Borlongan
Gary K. Steinberg

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.690613

3,345 views

Original Research

Published on 13 May 2021

Dual-Phase β-Amyloid PET Captures Neuronal Injury and Amyloidosis in Corticobasal Syndrome

in Cellular and Molecular Mechanisms of Brain-aging

Julia Schmitt
Carla Palleis
Julia Sauerbeck
Marcus Unterrainer
Stefanie Harris
Catharina Prix
Endy Weidinger
Sabrina Katzdobler
Olivia Wagemann
Adrian Danek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.661284

6,036 views
19 citations

Original Research

Published on 06 May 2021

Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice

in Cellular and Molecular Mechanisms of Brain-aging

Miao Zeng
Longkai Qi
Yinrui Guo
Xiangxiang Zhu
Xiaocui Tang
Tianqiao Yong
Yizhen Xie
Qingping Wu
Mei Zhang
Diling Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.628860

17,574 views
15 citations

Original Research

Published on 29 Apr 2021

Increased MANF Expression in the Inferior Temporal Gyrus in Patients With Alzheimer Disease

in Cellular and Molecular Mechanisms of Brain-aging

Xue-Chun Liu
Xiu-Hong Qi
Hui Fang
Ke-Qing Zhou
Qing-Song Wang
Gui-Hai Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.639318

4,386 views
17 citations

Review

Published on 28 Apr 2021

The Potential Role of Protein Kinase R as a Regulator of Age-Related Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Nicolás W. Martinez
Felipe E. Gómez
Soledad Matus

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.638208

7,281 views
27 citations

Review

Published on 09 Apr 2021

Neuregulins in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Guan-yong Ou
Wen-wen Lin
Wei-jiang Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.662474

11,817 views
51 citations

Mini Review

Published on 08 Apr 2021

Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue

in Cellular and Molecular Mechanisms of Brain-aging

Dmitry M. Hushpulian
Navneet Ammal Kaidery
Manuj Ahuja
Andrey A. Poloznikov
Sudarshana M. Sharma
Irina G. Gazaryan
Bobby Thomas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.673205

9,441 views
30 citations

Review

Published on 06 Apr 2021

The Emerging Role of the Interplay Among Astrocytes, Microglia, and Neurons in the Hippocampus in Health and Disease

in Cellular and Molecular Mechanisms of Brain-aging

Daniele Lana
Filippo Ugolini
Daniele Nosi
Gary L. Wenk
Maria Grazia Giovannini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.651973

10,222 views
52 citations

Review

Published on 06 Apr 2021

Transneuronal Degeneration in the Brain During Glaucoma

in Cellular and Molecular Mechanisms of Brain-aging

Mengling You
Rong Rong
Zhou Zeng
Xiaobo Xia
Dan Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.643685

9,419 views
42 citations

Original Research

Published on 22 Mar 2021

Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

in Cellular and Molecular Mechanisms of Brain-aging

Luciana Medina
Florencia González-Lizárraga
Antonio Dominguez-Meijide
Diego Ploper
Valeria Parrales
Sabrina Sequeira
Maria-Sol Cima-Omori
Markus Zweckstetter
Elaine Del Bel
Patrick P. Michel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.635760

9,159 views
20 citations

Original Research

Published on 17 Mar 2021

α-Synuclein Up-regulates Monoamine Oxidase A Expression and Activity via Trans-Acting Transcription Factor 1

in Cellular and Molecular Mechanisms of Brain-aging

Congcong Jia
Cheng Cheng
Tianbai Li
Xi Chen
Yuting Yang
Xinyao Liu
Song Li
Weidong Le

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.653379

4,242 views
11 citations

Original Research

Published on 16 Mar 2021

Absence of Pannexin 1 Stabilizes Hippocampal Excitability After Intracerebral Treatment With Aβ (1-42) and Prevents LTP Deficits in Middle-Aged Mice

in Cellular and Molecular Mechanisms of Brain-aging

Nicolina Südkamp
Olena Shchyglo
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.591735

4,030 views
11 citations