Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 28 Jul 2021

Effects of Lipotoxicity in Brain Microvascular Endothelial Cells During Sirt3 Deficiency-Potential Role in Comorbid Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Alpna Tyagi
Carol Mirita
Iman Shah
P. Hemachandra Reddy
Subbiah Pugazhenthi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.716616

6,291 views
17 citations

Review

Published on 15 Jul 2021

Research Progress on the Mechanism of Mitochondrial Autophagy in Cerebral Stroke

in Cellular and Molecular Mechanisms of Brain-aging

Li Lei
Shuaifeng Yang
Xiaoyang Lu
Yongfa Zhang
Tao Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.698601

6,543 views
18 citations

Review

Published on 13 Jul 2021

The Biology and Pathobiology of Glutamatergic, Cholinergic, and Dopaminergic Signaling in the Aging Brain

in Cellular and Molecular Mechanisms of Brain-aging

Anna Gasiorowska
Malgorzata Wydrych
Patrycja Drapich
Maciej Zadrozny
Marta Steczkowska
Wiktor Niewiadomski
Grazyna Niewiadomska

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.654931

31,501 views
116 citations

Mini Review

Published on 12 Jul 2021

The Emerging Role of Circular RNAs in Alzheimer’s Disease and Parkinson’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Meng Zhang
Zhigang Bian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.691512

8,009 views
35 citations

Review

Published on 08 Jul 2021

Cholesterol Hydroxylating Cytochrome P450 46A1: From Mechanisms of Action to Clinical Applications

in Cellular and Molecular Mechanisms of Brain-aging

Irina A. Pikuleva
Nathalie Cartier

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.696778

10,598 views
60 citations

Case Report

Published on 29 Jun 2021

Case Report: A Homozygous Mutation (p.Y62X) of Phospholipase D3 May Lead to a New Leukoencephalopathy Syndrome

in Cellular and Molecular Mechanisms of Brain-aging

Yi-Hui Liu
Hai-Feng Zhang
Jie-Yuan Jin
Yan-Qiu Wei
Chen-Yu Wang
Liang-Liang Fan
Lv Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.671296

3,387 views
4 citations

Review

Published on 25 Jun 2021

Alpha-Synuclein Post-translational Modifications: Implications for Pathogenesis of Lewy Body Disorders

in Cellular and Molecular Mechanisms of Brain-aging

Nelson de Oliveira Manzanza
Lucia Sedlackova
Raj N. Kalaria

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.690293

14,988 views
55 citations

Original Research

Published on 24 Jun 2021

Cadmium, an Environmental Contaminant, Exacerbates Alzheimer’s Pathology in the Aged Mice’s Brain

in Cellular and Molecular Mechanisms of Brain-aging

Tahir Ali
Amjad Khan
Sayed Ibrar Alam
Sareer Ahmad
Muhammad Ikram
Jun Sung Park
Hyeon Jin Lee
Myeong Ok Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.650930

5,890 views
34 citations

Mini Review

Published on 23 Jun 2021

The Role of Protein Persulfidation in Brain Aging and Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Dunja Petrovic
Emilia Kouroussis
Thibaut Vignane
Milos R. Filipovic

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.674135

9,855 views
52 citations

Review

Published on 23 Jun 2021

Stress Granules and Neurodegenerative Disorders: A Scoping Review

in Cellular and Molecular Mechanisms of Brain-aging

Mohammad Reza Asadi
Marziyeh Sadat Moslehian
Hani Sabaie
Abbas Jalaiei
Soudeh Ghafouri-Fard
Mohammad Taheri
Maryam Rezazadeh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.650740

14,630 views
32 citations

Original Research

Published on 18 Jun 2021

Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples

in Cellular and Molecular Mechanisms of Brain-aging

Laura N. Puentes
Zsofia Lengyel-Zhand
Ji Youn Lee
Chia-Ju Hsieh
Mark E. Schneider
Kimberly J. Edwards
Kelvin C. Luk
Virginia M.-Y. Lee
John Q. Trojanowski
Robert H. Mach

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.704041

5,734 views
20 citations

Mini Review

Published on 11 Jun 2021

The Unfolded Protein Response in Immune Cells as an Emerging Regulator of Neuroinflammation

in Cellular and Molecular Mechanisms of Brain-aging

Dominique Fernández
Antonia Geisse
Jose Ignacio Bernales
Alonso Lira
Fabiola Osorio

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.682633

6,751 views
31 citations

Review

Published on 08 Jun 2021

Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury

in Cellular and Molecular Mechanisms of Brain-aging

Luoan Shen
Qinyi Gan
Youcheng Yang
Cesar Reis
Zheng Zhang
Shanshan Xu
Tongyu Zhang
Chengmei Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.687246

17,538 views
96 citations

Brief Research Report

Published on 28 May 2021

Lack of Spinal Neuropeptide Y Is Involved in Mechanical Itch in Aged Mice

in Cellular and Molecular Mechanisms of Brain-aging

Huan Cui
Wenliang Su
Yan Cao
Lulu Ma
Guangyan Xu
Wanying Mou
Hanlin Zhang
Jiawen Yu
Chao Ma
Xiuhua Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.654761

4,660 views
5 citations

Original Research

Published on 28 May 2021

Decreased Exosomal Acetylcholinesterase Activity in the Plasma of Patients With Parkinson’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Kyu Hwan Shim
Han Gyeol Go
Heewon Bae
Da-Eun Jeong
Danyeong Kim
Young Chul Youn
SangYun Kim
Seong Soo A. An
Min Ju Kang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.665400

5,459 views
33 citations

Original Research

Published on 28 May 2021

Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging

in Cellular and Molecular Mechanisms of Brain-aging

Eunyoung Bang
Angelika Tobery
Karienn S. Montgomery
Annette S. Fincher
David J. Earnest
David A. Murchison
William H. Griffith

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.673155

8,872 views
9 citations