Original Research

Published on 28 Jun 2022

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

in Cellular and Molecular Mechanisms of Brain-aging

Frank W. Pun
Bonnie Hei Man Liu
Xi Long
Hoi Wing Leung
Geoffrey Ho Duen Leung
Quinlan T. Mewborne
Junli Gao
Anastasia Shneyderman
Ivan V. Ozerov
Ju Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.914017

34,388 views
50 citations

Review

Published on 28 Jun 2022

Mechanisms of Ferroptosis and Emerging Links to the Pathology of Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Yiyan Sun
Xiaohuan Xia
Diksha Basnet
Jialin C. Zheng
Jian Huang
Jianhui Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.904152

11,359 views
49 citations

Original Research

Published on 27 Jun 2022

The Big Picture of Neurodegeneration: A Meta Study to Extract the Essential Evidence on Neurodegenerative Diseases in a Network-Based Approach

in Cellular and Molecular Mechanisms of Brain-aging

Nicolas Ruffini
Susanne Klingenberg
Raoul Heese
Susann Schweiger
Susanne Gerber

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.866886

6,625 views
4 citations

Editorial

Published on 27 Jun 2022

Editorial: Genetic and Epigenetic Basis of Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Lamei Yuan
Yi Guo
Shu Wen
Hao Deng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.958847

1,655 views
3 citations

Original Research

Published on 20 Jun 2022

PCBP-1 Regulates the Transcription and Alternative Splicing of Inflammation and Ubiquitination-Related Genes in PC12 Cell

in Cellular and Molecular Mechanisms of Brain-aging

Aishanjiang Yusufujiang
Shan Zeng
Chen Yang
Sha Jing
Lijuan Yang
Hongyan Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.884837

5,562 views
11 citations

Original Research

Published on 16 Jun 2022

Exploration of Mutated Genes and Prediction of Potential Biomarkers for Childhood-Onset Schizophrenia Using an Integrated Bioinformatic Analysis

in Cellular and Molecular Mechanisms of Brain-aging

Fan He
Yu-ming Zhou
Yan-jie Qi
Huan-huan Huang
Lin Guan
Jie Luo
Yu-hang Cheng
Yi Zheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.829217

2,241 views
3 citations

Review

Published on 13 Jun 2022

A Comprehensive Overview of the Complex Role of Oxidative Stress in Aging, The Contributing Environmental Stressors and Emerging Antioxidant Therapeutic Interventions

in Cellular and Molecular Mechanisms of Brain-aging

Evripides Iakovou
Malamati Kourti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.827900

11,337 views
38 citations

Editorial

Published on 08 Jun 2022

Editorial: Genomic Instability and Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Julia Fuchs
Bjoern Schwer
Sherif F. El-Khamisy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.940459

2,483 views
2 citations

Review

Published on 03 Jun 2022

Melatonin as an Anti-Aging Therapy for Age-Related Cardiovascular and Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Virna Margarita Martín Giménez
Natalia de las Heras
Vicente Lahera
Jesús A. F. Tresguerres
Russel J. Reiter
Walter Manucha

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.888292

33,360 views
29 citations

Review

Published on 30 May 2022

A Systematic Review of Body Fluids Biomarkers Associated With Early Neurological Deterioration Following Acute Ischemic Stroke

in Cellular and Molecular Mechanisms of Brain-aging

Xiaotan Ji
Long Tian
Shumei Yao
Fengyue Han
Shenna Niu
Chuanqiang Qu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.918473

6,114 views
18 citations

Opinion

Published on 26 May 2022

The Role of Alpha-Synuclein Autoantibodies in the Induction of Brain Inflammation and Neurodegeneration in Aged Humans

in Cellular and Molecular Mechanisms of Brain-aging

Manoj Kumar Pandey

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.902191

1,783 views
4 citations

Systematic Review

Published on 23 May 2022

Effects of Intermittent Hypoxia in Training Regimes and in Obstructive Sleep Apnea on Aging Biomarkers and Age-Related Diseases: A Systematic Review

in Cellular and Molecular Mechanisms of Brain-aging

Belay Tessema
Ulrich Sack
Brigitte König
Zoya Serebrovska
Egor Egorov

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.878278

8,738 views
13 citations

Review

Published on 19 May 2022

Astrocyte Reprogramming in Stroke: Opportunities and Challenges

in Cellular and Molecular Mechanisms of Brain-aging

Zhouzhou Peng
Hui Lu
Qingwu Yang
Qi Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.885707

4,898 views
7 citations

Review

Published on 19 May 2022

Neuroinflammation: A Possible Link Between Chronic Vascular Disorders and Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Emmanuel Moyse
Slavica Krantic
Nesrine Djellouli
Sébastien Roger
Denis Angoulvant
Camille Debacq
Victoire Leroy
Bertrand Fougere
Amal Aidoud

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.827263

11,236 views
39 citations

Editorial

Published on 17 May 2022

Editorial: Role of Senescence in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Ferit Tüzer
Shankar J. Chinta
Tania Araujo Viel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.907670

1,581 views

Review

Published on 09 May 2022

Regulation of Mitophagy by Sirtuin Family Proteins: A Vital Role in Aging and Age-Related Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Wei Wan
Fuzhou Hua
Pu Fang
Chang Li
Fumou Deng
Shoulin Chen
Jun Ying
Xifeng Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.845330

8,550 views
34 citations

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Articles

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Mechanisms of Ferroptosis and Emerging Links to the Pathology of Neurodegenerative Diseases

The Big Picture of Neurodegeneration: A Meta Study to Extract the Essential Evidence on Neurodegenerative Diseases in a Network-Based Approach

Editorial: Genetic and Epigenetic Basis of Neurodegenerative Diseases

PCBP-1 Regulates the Transcription and Alternative Splicing of Inflammation and Ubiquitination-Related Genes in PC12 Cell

Exploration of Mutated Genes and Prediction of Potential Biomarkers for Childhood-Onset Schizophrenia Using an Integrated Bioinformatic Analysis

A Comprehensive Overview of the Complex Role of Oxidative Stress in Aging, The Contributing Environmental Stressors and Emerging Antioxidant Therapeutic Interventions

Editorial: Genomic Instability and Neurodegeneration

Melatonin as an Anti-Aging Therapy for Age-Related Cardiovascular and Neurodegenerative Diseases

A Systematic Review of Body Fluids Biomarkers Associated With Early Neurological Deterioration Following Acute Ischemic Stroke

The Role of Alpha-Synuclein Autoantibodies in the Induction of Brain Inflammation and Neurodegeneration in Aged Humans

Effects of Intermittent Hypoxia in Training Regimes and in Obstructive Sleep Apnea on Aging Biomarkers and Age-Related Diseases: A Systematic Review

Astrocyte Reprogramming in Stroke: Opportunities and Challenges

Neuroinflammation: A Possible Link Between Chronic Vascular Disorders and Neurodegenerative Diseases

Editorial: Role of Senescence in Neurodegenerative Diseases

Regulation of Mitophagy by Sirtuin Family Proteins: A Vital Role in Aging and Age-Related Diseases