Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 13 Feb 2025

Investigation of protective effects of olanzapine on impaired learning and memory using behavioral tests in a rat model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Somayeh Komaki
Parsa Amiri
Samaneh Safari
Ebrahim Abbasi
Fatemeh Ramezani-Aliakbari
Mandana Golipoor
Masoumeh Kourosh-Arami
Masome Rashno
Alireza Komaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1376074

1,388 views

Original Research

Published on 13 Feb 2025

Deciphering novel mitochondrial signatures: multi-omics analysis uncovers cross-disease markers and oligodendrocyte pathways in Alzheimer’s disease and glioblastoma

in Alzheimer's Disease and Related Dementias

Xuan Xu
Jiaqi Wang
Tong Chen
Shuaibin Wang
Fei Wang
Junwen He
Xiang-Yu Meng
Yin Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1536142

2,085 views

Review

Published on 13 Feb 2025

Non-pharmacological treatment of Alzheimer’s disease: an update

in Alzheimer's Disease and Related Dementias

Shaofen Wang
Haochen Xu
Guangdong Liu
Limei Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527242

2,095 views
1 citation

Original Research

Published on 12 Feb 2025

Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo

in Alzheimer's Disease and Related Dementias

Jean Ikanga
Saranya Sundaram Patel
Megan Schwinne
Caterina Obenauf
Emmanuel Epenge
Guy Gikelekele
Nathan Tshengele
Immaculee Kavugho
Samuel Mampunza
Lelo Mananga

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552348

1,187 views

Brief Research Report

Published on 10 Feb 2025

Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy

in Alzheimer's Disease and Related Dementias

Danielle Sidsworth
Noah Tregobov
Colin Jamieson
Jennifer Reutens-Hernandez
Joshua Yoon
Geoffrey W. Payne
Stephanie L. Sellers

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1482250

1,026 views

Correction

Published on 07 Feb 2025

Corrigendum: Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review

in Alzheimer's Disease and Related Dementias

Jiangfeng Liao
Wenming Hu
Shiheng Chen
Chunyu Huang
Senwei Dong
Wanjin Chen
Xiaochun Chen
Longfei Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565464

1,008 views

Original Research

Published on 04 Feb 2025

Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yan Wu
Narayan R. Bhat
Meng Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529769

1,457 views

Original Research

Published on 03 Feb 2025

Nomogram for predicting mild cognitive impairment in Chinese elder CSVD patients based on Boruta algorithm

in Alzheimer's Disease and Related Dementias

Yanzi Huang
Wendie Huang
Xiaoming Ma
Guoyin Zhao
Jingwen Kang
Huajie Li
Jingwei Li
Shiying Sheng
Fengjuan Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1431421

1,182 views

Original Research

Published on 03 Feb 2025

Ketamine does not rescue plaque load or gap detection in the 5XFAD mouse model of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Alexa L. Wright
Aldis P. Weible
Olivia B. Estes
Michael Wehr

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505908

1,312 views

Review

Published on 29 Jan 2025

Multi-functional role of apolipoprotein E in neurodegenerative diseases

in Alzheimer's Disease and Related Dementias

Sadequl Islam
Arshad Noorani
Yang Sun
Makoto Michikawa
Kun Zou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1535280

2,594 views

Systematic Review

Published on 29 Jan 2025

Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of randomized controlled trials

in Alzheimer's Disease and Related Dementias

Wenting Cai
Hui Zhang
Yan Wu
Yao Yao
Jinping Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1465871

1,554 views
1 citation

Original Research

Published on 28 Jan 2025

Hypertension moderates the relationship between plasma beta-amyloid and cognitive impairment: a cross-sectional study in Xi’an, China

in Alzheimer's Disease and Related Dementias

Ziyu Liu
Yaoli He
Simeng Cui
Liangjun Dang
Binyan Zhang
Jin Wang
Wenhui Lu
Kang Huo
Yu Jiang
Chen Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1532676

900 views

Systematic Review

Published on 28 Jan 2025

Imaging markers of cerebral small vessel disease are associated with Alzheimer’s disease: a systematic review and meta-analysis

in Alzheimer's Disease and Related Dementias

Qi Wu
Jupeng Zhang
Peng Lei
Xiqi Zhu
Changhui Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1498636

623 views

Original Research

Published on 27 Jan 2025

Untargeted urine metabolomics reveals dynamic metabolic differences and key biomarkers across different stages of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Xiaoya Feng
Shenglan Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1530046

1,193 views

Original Research

Published on 23 Jan 2025

Diagnostic potential of urinary CX3CL1 for amnestic mild cognitive impairment and Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yali Xu
Jie Zhang
Ying-Ying Shen
Wei-Wei Li
Bin Li
Hai-Ping Cheng
Gui-Hua Zeng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1501762

778 views

Original Research

Published on 22 Jan 2025

Lingguizhugan decoction enhances autophagy of Alzheimer’s disease via regulating the mTOR/ p70s6K pathway in vivo and in vitro

in Alzheimer's Disease and Related Dementias

Xiaojing Chen
Qingrong Tian
Min Gao
Xibin Zhou
Chunxiang Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1478199

1,073 views
1 citation