Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 14 Aug 2024

Deep learning-based quantification of brain atrophy using 2D T1-weighted MRI for Alzheimer’s disease classification

in Alzheimer's Disease and Related Dementias

Chae Jung Park
Yu Hyun Park
Kichang Kwak
Soohwan Choi
Hee Jin Kim
Duk L. Na
Sang Won Seo
Min Young Chun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423515

4,890 views

Original Research

Published on 12 Aug 2024

Characterizing the clinical heterogeneity of early symptomatic Alzheimer’s disease: a data-driven machine learning approach

in Alzheimer's Disease and Related Dementias

Xiwu Wang
Teng Ye
Deguo Jiang
Wenjun Zhou
Jie Zhang
for the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1410544

1,907 views
1 citation

Original Research

Published on 09 Aug 2024

Modeling APOE ε4 familial Alzheimer’s disease in directly converted 3D brain organoids

in Alzheimer's Disease and Related Dementias

Yunkyung Kim
Hongwon Kim
Byounggook Cho
Saemin An
Soi Kang
Sumin Kim
Jongpil Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1435445

2,449 views
3 citations

Review

Published on 09 Aug 2024

Alzheimer’s disease: a review on the current trends of the effective diagnosis and therapeutics

in Alzheimer's Disease and Related Dementias

Aimi Syamima Abdul Manap
Reema Almadodi
Shirin Sultana
Maheishinii Grace Sebastian
Kenil Sureshbhai Kavani
Vanessa Elle Lyenouq
Aravind Shankar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1429211

9,789 views
8 citations

Original Research

Published on 08 Aug 2024

O-GlcNAc impacts mitophagy via the PINK1-dependent pathway

in Alzheimer's Disease and Related Dementias

Ibtihal M. Alghusen
Marisa S. Carman
Heather M. Wilkins
Taylor A. Strope
Caleb Gimore
Halyna Fedosyuk
Jad Shawa
Sophiya John Ephrame
Aspin R. Denson
Xiaowan Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1387931

4,149 views
1 citation

Systematic Review

Published on 08 Aug 2024

Gut microbiota changes in patients with Alzheimer’s disease spectrum based on 16S rRNA sequencing: a systematic review and meta-analysis

in Alzheimer's Disease and Related Dementias

Hui Li
Xiaopan Cui
Yuxiu Lin
Fengqiong Huang
Ayong Tian
Rongwei Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1422350

3,563 views
4 citations

Original Research

Published on 07 Aug 2024

The involvement of effector memory CD4+ T cells in mediating the impact of genus Oscillibacter gut microbiota on Alzheimer’s disease: a Mendelian randomization study

in Alzheimer's Disease and Related Dementias

Huachang Zhang
Yudong Wang
Hui Zhao
Wei Wang
Fabin Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423707

2,215 views
1 citation

Original Research

Published on 07 Aug 2024

Association of peak expiratory flow with motoric cognitive risk syndrome among older adults

in Alzheimer's Disease and Related Dementias

Hui Xu
Xiangwen Gong
Kaiwang Cui
Xuerui Li
Long Chen
Yiyi Lu
Yangfang Liao
Jianping Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1412542

2,298 views

Original Research

Published on 06 Aug 2024

The association between rs6859 in NECTIN2 gene and Alzheimer’s disease is partly mediated by pTau

in Alzheimer's Disease and Related Dementias

Aravind Lathika Rajendrakumar
Konstantin G. Arbeev
Olivia Bagley
Anatoliy I. Yashin
Svetlana Ukraintseva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1388363

1,586 views
3 citations

Original Research

Published on 02 Aug 2024

Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1–42) profoundly and progressively alters brain function throughout life

in Alzheimer's Disease and Related Dementias

Marco Kramer
Thu-Huong Hoang
Honghong Yang
Olena Shchyglo
Juliane Böge
Ute Neubacher
Jens Colitti-Klausnitzer
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1397901

1,569 views

Original Research

Published on 02 Aug 2024

Senescence-related genes and proteins in the development of Alzheimer’s disease: evidence from transcriptomic and Mendelian randomization analysis

in Alzheimer's Disease and Related Dementias

Ying Liu
Jiao Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423725

2,767 views

Original Research

Published on 24 Jul 2024

Association of liver function markers and apolipoprotein E ε4 with pathogenesis and cognitive decline in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Sang-Won Han
Sang-Hwa Lee
Jong Ho Kim
Jae-Jun Lee
Young Ho Park
SangYun Kim
Kwangsik Nho
Jong-Hee Sohn

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1411466

2,413 views
1 citation

Original Research

Published on 23 Jul 2024

Correlation of brain tissue volume loss with inflammatory biomarkers IL1β, P-tau, T-tau, and NLPR3 in the aging cognitively impaired population

in Alzheimer's Disease and Related Dementias

Kyung Mi Lee
Sang Tae Kim
Yunan Tian
Sue Min Jung
Yunjung Chang
Hak Young Rhee
Soonchan Park
Chang-Woo Ryu
Woo-In Lee
Eui Jong Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1388654

1,823 views

Review

Published on 22 Jul 2024

Cognitive dysfunction in animal models of human lewy-body dementia

in Alzheimer's Disease and Related Dementias

Caroline Haikal
Graham M. Winston
Michael G. Kaplitt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1369733

2,282 views
2 citations

Review

Published on 17 Jul 2024

The relationship between hypoxia and Alzheimer’s disease: an updated review

in Alzheimer's Disease and Related Dementias

Borui Tao
Wei Gong
Chengyuan Xu
Zhihui Ma
Jinyu Mei
Ming Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1402774

3,226 views
3 citations

Original Research

Published on 17 Jul 2024

Identification of deregulated lncRNAs in Alzheimer’s disease: an integrated gene co-expression network analysis of hippocampus and fusiform gyrus RNA-seq datasets

in Alzheimer's Disease and Related Dementias

Ermes Filomena
Ernesto Picardi
Apollonia Tullo
Graziano Pesole
Anna Maria D’Erchia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1437278

2,008 views
1 citation