Frontiers in Aging Neuroscience

Original Research

Accepted on 11 Apr 2025

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Zhen Wei
Xiao-Dong Pan
Xiaoli Cui
Jing Zhang
Xiaoman Dai
Yuqi Zeng
Xiaochun Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1537388

Original Research

Accepted on 11 Apr 2025

Lower CALLY index levels indicate higher poor functional outcome risk in acute ischemic stroke patients treated with endovascular thrombectomy

in Neuroinflammation and Neuropathy

Yunnan Lu
Xiaohua Zhu
Yaojia Xu
Yongxin Li
Qingyong Dai
Xia Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587861

Original Research

Accepted on 11 Apr 2025

Effects of off-line auricular transcutaneous vagus nerve stimulation (taVNS) on a short-term memory task: a pilot study

in Neurocognitive Aging and Behavior

Francesco Fisicaro
Klizia Cortese
Rita Bella
Manuela Pennisi
Giuseppe Lanza
Kaoru Yuasa
Yoshikazu Ugawa
Yasuo Terao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549167

Original Research

Published on 11 Apr 2025

Normative characterization of age-related periodic and aperiodic activity in resting-state real-world clinical EEG recordings

in Neurocognitive Aging and Behavior

Sophie Leroy
Viktor Bublitz
Falk von Dincklage
Daria Antonenko
Robert Fleischmann

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540040

166 views

Original Research

Published on 11 Apr 2025

Bundled assessment to replace on-road test on driving function in stroke patients: a binary classification model via random forest

in Neurocognitive Aging and Behavior

Lu Huang
Xin Liu
Jiang Yi
Yu-Wei Jiao
Tian-Qi Zhang
Guang-Yao Zhu
Shu-Yue Yu
Zhong-Liang Liu
Min Gao
Xiao-Qin Duan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1503672

108 views

Original Research

Published on 11 Apr 2025

Uncovering unseen ties: a network analysis explores activities of daily living limitations and depression among Chinese older adults

in Neurocognitive Aging and Behavior

Hongbo Sun
Youcai Zhou
Xianqiang Zhang
Zhongxin Liang
Jinlan Chen
Ping Zhou
Xinjie Xue

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527774

146 views

Original Research

Published on 11 Apr 2025

Explainable graph neural network based on metabolic brain imaging for differential diagnosis of parkinsonism

in Neurocognitive Aging and Behavior

Ronghua Ling
Xingxing Cen
Shaoyou Wu
Min Wang
Ying Zhang
Juanjuan Jiang
Jiaying Lu
Yingqian Liu
Chuantao Zuo
Jiehui Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1580910

104 views

Original Research

Published on 11 Apr 2025

Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation

in Neurocognitive Aging and Behavior

Meixi Li
Jiaxi Song
Xiaoli Niu
Feng Mo
Xiaohua Xie
Xiuqin Li
Yu Yin
Tianjun Wang
Xiujuan Song
Jingze Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1521353

126 views

Original Research

Accepted on 10 Apr 2025

Relationship between the hemoglobin-to-red cell distribution width ratio and post-stroke cognitive impairment: A prospective study

in Neurocognitive Aging and Behavior

Yufeng Liu
Zhe Xie
Ping Wang
Fan Liu
Liandong Zhao
Chun Chen
Qiu Ge
Mengchao Wang
Zhongwen Zhi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552956

Original Research

Accepted on 10 Apr 2025

Effects of cannabidiol (CBD) treatments on age-related cognitive decline in C57 mice

in Neurocognitive Aging and Behavior

Behroo Mirza Agha
Merrin Monteith
Jarem Earl
Keona Ganske
Tina Kaloa
Kelan J Mcdonald
Abigail Nixon
Maleeha Panjwani
Danika Robinson
Valeria Rusnak

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1567650

Systematic Review

Published on 10 Apr 2025

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

in Alzheimer's Disease and Related Dementias

Serena Dattola
Augusto Ielo
Giuseppe Varone
Alberto Cacciola
Angelo Quartarone
Lilla Bonanno

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547727

300 views

Original Research

Accepted on 09 Apr 2025

Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury

in Neuroinflammation and Neuropathy

Bin Ren
Jifang Liang
Yang Leifang
Xiaocong Wei
Min Guo
Li Hong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1531317

Mini Review

Accepted on 09 Apr 2025

The potential and challenges of TREM2-targeted therapy in Alzheimer's disease: Insights from the INVOKE-2 study

in Alzheimer's Disease and Related Dementias

Ya-nan Ma
Xiqi Hu
Kenji Karako
Peipei Song
Takashi Karako
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1576020

Original Research

Accepted on 09 Apr 2025

Handgrip Strength and Risk of Cognitive Impairment Across Different Glucose Metabolism Statuses: Insights from the CHARLS Study

in Neurocognitive Aging and Behavior

Shiqi Wang
Liangchen Li
Jia Yu
Xianli Sun
Jianqiao Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566652

Correction

Published on 09 Apr 2025

Corrigendum: Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in parkinsonian brain via an Nrf2-driven Wnt/β-catenin prosurvival axis

in Parkinson’s Disease and Aging-related Movement Disorders

Maria Francesca Serapide
Francesca L'Episcopo
Cataldo Tirolo
Nunzio Testa
Salvatore Caniglia
Carmela Giachino
Bianca Marchetti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1596878

201 views

Systematic Review

Published on 09 Apr 2025

Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review

in Neurocognitive Aging and Behavior

Bo Yang
Xia Deng
Xianfeng Qu
Yingjie Li
Lei Guo
Nengwei Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1492800

223 views